Cheap Flights from Louisville, KY to Key West, FL from $83

Page navigation
Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 59 connecting flights from Louisville to Key West. You can compare airfare deals from 4 airlines and multiple travel sites from $83, book and save on cheap plane tickets and last minute offers. Also check out SDF-EYW flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Louisville to Key West Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $83 (one-way), $142 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights

Best Flights from Louisville to Key West Today

Take a look at the list of non stop flights and flights with layovers from Louisville to Key West with the lowest price of $83. Take a look at the list of flights with layovers from Louisville to Key West from $83. There’re no direct flights. The fastest connecting flight – 6h 11m.
Price Departure Arrival Flight Duration Airline Flight
from $83
Find flight
15:47
Louisville
Standiford Field
 14:44+1 день
Key West
Key West Int.
 22h 57m
layover
19h 53m - Clearwater
 Allegiant Air
G41099
G41048
from $98
Find flight
15:07
Louisville
Standiford Field
 15:08+1 день
Key West
Key West Int.
 24h 1m
layover
20h 56m - Clearwater
 Spirit Airlines
NK2159
G41034
from $134
Find flight
13:35
Louisville
Standiford Field
 09:43+1 день
Key West
Key West Int.
 20h 8m
layover
5h 15m - Myrtle Beach
10h 42m - Sanford
 Spirit Airlines
NK2751
NK2089
G42877
from $144
Find flight
11:34
Louisville
Standiford Field
 16:36+1 день
Key West
Key West Int.
 29h 2m
layover
7h 22m - Punta Gorda
14h 18m - Pittsburgh
 Allegiant Air
G41451
G42750
G4991
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 15, 2025
Full flight schedule will help you in detecting at what time planes fly from Louisville to Key West. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
10:54 — 16:45
+1 day
10:54 — 12:21 G42969 Allegiant Air
Louisville — Myrtle Beach
9h 30m stop
21:51 — 23:36 G4631 Allegiant Air
Myrtle Beach — Indianapolis
14h 28m stop
14:04 — 16:45 G41285 Allegiant Air
Indianapolis — Key West
29h 51m
including layover
Find flight
from$153
11:04 — 15:08
+1 day
11:04 — 12:22 NK2795 Spirit Airlines
Louisville — Detroit
2h 4m stop
14:26 — 17:08 NK2739 Spirit Airlines
Detroit — Clearwater
20h 57m stop
14:05 — 15:08 G41034 Allegiant Air
Clearwater — Key West
28h 4m
including layover
Find flight
from$137
11:34 — 16:36
+1 day
11:34 — 13:49 G41451 Allegiant Air
Louisville — Punta Gorda
7h 22m stop
21:11 — 23:36 G42750 Allegiant Air
Punta Gorda — Pittsburgh
14h 18m stop
13:54 — 16:36 G4991 Allegiant Air
Pittsburgh — Key West
29h 2m
including layover
Find flight
from$144
11:34 — 16:36
+1 day
11:34 — 13:49 G43088 Allegiant Air
Louisville — Punta Gorda
7h 26m stop
21:15 — 23:39 G42737 Allegiant Air
Punta Gorda — Pittsburgh
14h 15m stop
13:54 — 16:36 G41055 Allegiant Air
Pittsburgh — Key West
29h 2m
including layover
Find flight
from$157
12:32 — 16:36
+1 day
12:32 — 14:54 NK1785 Spirit Airlines
Louisville — Newark
7h 11m stop
22:05 — 23:29 NK1788 Spirit Airlines
Newark — Pittsburgh
14h 25m stop
13:54 — 16:36 G41055 Allegiant Air
Pittsburgh — Key West
28h 4m
including layover
Find flight
from$161
13:35 — 09:43
+1 day
13:35 — 15:09 NK2751 Spirit Airlines
Louisville — Myrtle Beach
5h 15m stop
20:24 — 21:50 NK2089 Spirit Airlines
Myrtle Beach — Sanford
10h 42m stop
08:32 — 09:43 G42877 Allegiant Air
Sanford — Key West
20h 8m
including layover
Find flight
from$134
13:35 — 16:45
+1 day
13:35 — 15:09 NK2751 Spirit Airlines
Louisville — Myrtle Beach
6h 42m stop
21:51 — 23:36 G4631 Allegiant Air
Myrtle Beach — Indianapolis
14h 28m stop
14:04 — 16:45 G41285 Allegiant Air
Indianapolis — Key West
27h 10m
including layover
Find flight
from$167
15:07 — 15:08
+1 day
15:07 — 17:09 NK2159 Spirit Airlines
Louisville — Clearwater
20h 56m stop
14:05 — 15:08 G41034 Allegiant Air
Clearwater — Key West
24h 1m
including layover
Find flight
from$98
15:07 — 08:04
+1 day
15:07 — 17:09 NK2159 Spirit Airlines
Louisville — Clearwater
13h 51m stop
07:00 — 08:04 G4971 Allegiant Air
Clearwater — Key West
16h 57m
including layover
Find flight
from$110
15:36 — 09:43
+1 day
15:36 — 17:36 G42832 Allegiant Air
Louisville — Sanford
14h 56m stop
08:32 — 09:43 G42877 Allegiant Air
Sanford — Key West
18h 7m
including layover
Find flight
from$104
15:47 — 14:44
+1 day
15:47 — 17:47 G41099 Allegiant Air
Louisville — Clearwater
19h 53m stop
13:40 — 14:44 G41048 Allegiant Air
Clearwater — Key West
22h 57m
including layover
Find flight
from$83
15:52 — 15:08
+1 day
15:52 — 17:52 G41099 Allegiant Air
Louisville — Clearwater
20h 13m stop
14:05 — 15:08 G41034 Allegiant Air
Clearwater — Key West
23h 16m
including layover
Find flight
from$91
17:34 — 09:43
+1 day
17:34 — 19:48 NK2610 Spirit Airlines
Louisville — Sanford
12h 44m stop
08:32 — 09:43 G42877 Allegiant Air
Sanford — Key West
16h 9m
including layover
Find flight
from$121
18:04 — 18:42
+1 day
18:04 — 20:19 G42482 Allegiant Air
Louisville — Punta Gorda
16h 15m stop
12:34 — 14:19 G41840 Allegiant Air
Punta Gorda — Fletcher
2h 24m stop
16:43 — 18:42 G4228 Allegiant Air
Fletcher — Key West
24h 38m
including layover
Find flight
from$148
18:57 — 09:22
+1 day
18:57 — 21:07 MX105 Mexicana
Louisville — Tampa
11h 8m stop
08:15 — 09:22 MX160 Mexicana
Tampa — Key West
14h 25m
including layover
Find flight
from$115
*Departure and arrival times - local. Updated on September 15, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Louisville to Key West depends on and how to choose the most interesting flight option for you.

Distance between Louisville and Key West is 1560 miles. Time difference between the cities is 0h. Airplanes depart 05:03 to 20:35 from 3 Louisville airports and arrive 05:03 to 20:35 to 2 Key West airports. Average flight time is 23h 53m.

  • The fastest flight 6h 11m
  • Average flight time 23h 53m
  • The earliest flight 05:03
  • The latest flight 20:35
  • Distance 970 ml

The cheapest months to travel to Key West are august (from 83 $), july (from 91 $), september (from 148 $).

The most expensive months are october (from 229 $), september (from 148 $), july (from 91 $).

What is the lowest airfare Louisville to Key West?

The cheapest plane ticket found by our users is $83. This airfare is for economy class on one-way G41099 flight by Allegiant Air for August 8, 2025 which leaves Standiford Field in Louisville at 15:47 am and arrives at Key West Key West Int. at 14:44.

Economy class
$83
Find
Business class
?
Find
First class
?
Find

Popular Airlines on the Route

The flight Louisville — Key West is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Mexicana - 8 departures per week at the price of from $ 115 . And the most expensive tickets are offered by United Airlines airline - from $ 693.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 59 flights with layovers on the route. The fastest connecting flight is UA3594 by United Airlines takes 6h 11m and the cheapest is G41099 by Allegiant Air for $83.

  • MX - Mexicana
    from $115
    Find
  • UA - United Airlines
    from $229
    Find
  • G4 - Allegiant Air
    from $83
    Find
  • NK - Spirit Airlines
    from $98
    Find
See more connecting flights

Airports

You can fly from Louisville to Key West from 3 airports (Standiford Field, Intercontinental, Bowman Field).

Louisville airports

  • Standiford Field-SDF
    from $83
    Find
  • Intercontinental-LJC
    Find
  • Bowman Field-LOU
    Find

Key West airports

  • NAS-NQX
    Find
  • Key West Int.-EYW
    Find

Airplanes

There are flights to Key West from Louisville by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Louisville

You may also consider searching for discounted plane tickets to some other popular places from Louisville within United States.

Top International Destinations from Louisville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back