Cheap Flights from Louisville, KY to Key West, FL from $86
On Cheapflightsplus.com you will find 59 connecting flights from Louisville to Key West. You can compare airfare deals from 4 airlines and multiple travel sites from $86, book and save on cheap plane tickets and last minute offers. Also check out SDF-EYW flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Louisville to Key West Flight Deals
Best Flights from Louisville to Key West Today
Price | Departure | Arrival | Flight Duration | Airline | Flight |
---|---|---|---|---|---|
from $86 | 15:47 Louisville Standiford Field | 14:44+1 день Key West Key West Int. | 22h 57m layover 19h 53m - Clearwater | Allegiant Air | G41099 G41048 |
from $102 | 15:07 Louisville Standiford Field | 15:08+1 день Key West Key West Int. | 24h 1m layover 20h 56m - Clearwater | Spirit Airlines | NK2159 G41034 |
from $109 | 15:36 Louisville Standiford Field | 09:43+1 день Key West Key West Int. | 18h 7m layover 14h 56m - Sanford | Allegiant Air | G42832 G42877 |
from $120 | 18:57 Louisville Standiford Field | 09:22+1 день Key West Key West Int. | 14h 25m layover 11h 8m - Tampa | Mexicana | MX105 MX160 |
from $126 | 17:34 Louisville Standiford Field | 09:43+1 день Key West Key West Int. | 16h 9m layover 12h 44m - Sanford | Spirit Airlines | NK2610 G42877 |
from $180 | 18:57 Louisville Standiford Field | 09:33+1 день Key West Key West Int. | 14h 36m layover 11h 23m - Clearwater | Mexicana | MX105 G4971 |
from $193 | 17:34 Louisville Standiford Field | 13:07+1 день Key West Key West Int. | 19h 33m layover 16h 4m - Orlando | Spirit Airlines | NK2610 MX162 |
from $140 | 13:35 Louisville Standiford Field | 09:43+1 день Key West Key West Int. | 20h 8m layover 5h 15m - Myrtle Beach 10h 42m - Sanford | Spirit Airlines | NK2751 NK2089 G42877 |
from $143 | 11:04 Louisville Standiford Field | 15:08+1 день Key West Key West Int. | 28h 4m layover 2h 4m - Detroit 20h 57m - Clearwater | Spirit Airlines | NK2795 NK2739 G41034 |
from $150 | 11:34 Louisville Standiford Field | 16:36+1 день Key West Key West Int. | 29h 2m layover 7h 22m - Punta Gorda 14h 18m - Pittsburgh | Allegiant Air | G41451 G42750 G4991 |
from $155 | 18:04 Louisville Standiford Field | 18:42+1 день Key West Key West Int. | 24h 38m layover 16h 15m - Punta Gorda 2h 24m - Fletcher | Allegiant Air | G42482 G41840 G4228 |
from $160 | 10:54 Louisville Standiford Field | 16:45+1 день Key West Key West Int. | 29h 51m layover 9h 30m - Myrtle Beach 14h 28m - Indianapolis | Allegiant Air | G42969 G4631 G41285 |
from $164 | 11:34 Louisville Standiford Field | 16:36+1 день Key West Key West Int. | 29h 2m layover 7h 26m - Punta Gorda 14h 15m - Pittsburgh | Allegiant Air | G43088 G42737 G41055 |
from $168 | 12:32 Louisville Standiford Field | 16:36+1 день Key West Key West Int. | 28h 4m layover 7h 11m - Newark 14h 25m - Pittsburgh | Spirit Airlines | NK1785 NK1788 G41055 |
from $192 | 17:43 Louisville Standiford Field | 15:16+1 день Key West Key West Int. | 21h 33m layover 12h 51m - Fort Walton Beach 2h 33m - Covington | Allegiant Air | G41490 G43069 G4426 |
from $195 | 17:43 Louisville Standiford Field | 16:36+1 день Key West Key West Int. | 22h 53m layover 14h 8m - Fort Walton Beach 2h 14m - Pittsburgh | Allegiant Air | G41490 G42725 G41055 |
Flight Schedule Louisville (Kentucky) to Key West (Florida)
Departure | Arrival | Flight Details | Flight Duration | Price |
---|---|---|---|---|
06:15 — 14:11
|
06:15 — 08:30
UA3594
United Airlines
Louisville — Newark
2h 10m stop
10:40 — 14:11
UA3687
United Airlines
Newark — Key West
|
7h 56m including layover |
Find flight
from$284 |
|
06:30 — 12:41
|
06:30 — 08:42
UA3594
United Airlines
Louisville — Newark
47m stop
09:29 — 12:41
UA1822
United Airlines
Newark — Key West
|
6h 11m including layover |
Find flight
from$280 |
|
09:06 — 08:15
+1 day
|
09:06 — 11:15
NK143
Spirit Airlines
Louisville — Orlando
19h 45m stop
07:00 — 08:15
MX159
Mexicana
Orlando — Key West
|
23h 9m including layover |
Find flight
from$260 |
|
15:47 — 14:44
+1 day
|
15:47 — 17:47
G41099
Allegiant Air
Louisville — Clearwater
19h 53m stop
13:40 — 14:44
G41048
Allegiant Air
Clearwater — Key West
|
22h 57m including layover |
Find flight
from$86 |
|
15:52 — 15:08
+1 day
|
15:52 — 17:52
G41099
Allegiant Air
Louisville — Clearwater
20h 13m stop
14:05 — 15:08
G41034
Allegiant Air
Clearwater — Key West
|
23h 16m including layover |
Find flight
from$95 |
|
17:34 — 09:43
+1 day
|
17:34 — 19:48
NK2610
Spirit Airlines
Louisville — Sanford
12h 44m stop
08:32 — 09:43
G42877
Allegiant Air
Sanford — Key West
|
16h 9m including layover |
Find flight
from$126 |
|
18:57 — 09:22
+1 day
|
18:57 — 21:07
MX105
Mexicana
Louisville — Tampa
11h 8m stop
08:15 — 09:22
MX160
Mexicana
Tampa — Key West
|
14h 25m including layover |
Find flight
from$120 |
|
05:03 — 13:07
+1 day
|
05:03 — 07:25
NK2716
Spirit Airlines
Louisville — Miami
22h 50m stop
06:15 — 07:18
NK2195
Spirit Airlines
Miami — Orlando
4h 34m stop
11:52 — 13:07
MX162
Mexicana
Orlando — Key West
|
32h 4m including layover |
Find flight
from$258 |
|
05:03 — 13:07
+1 day
|
05:03 — 07:25
NK2716
Spirit Airlines
Louisville — Miami
11h 50m stop
19:15 — 20:24
NK2008
Spirit Airlines
Miami — Orlando
15h 28m stop
11:52 — 13:07
MX162
Mexicana
Orlando — Key West
|
32h 4m including layover |
Find flight
from$298 |
|
10:54 — 16:45
+1 day
|
10:54 — 12:21
G42969
Allegiant Air
Louisville — Myrtle Beach
9h 30m stop
21:51 — 23:36
G4631
Allegiant Air
Myrtle Beach — Indianapolis
14h 28m stop
14:04 — 16:45
G41285
Allegiant Air
Indianapolis — Key West
|
29h 51m including layover |
Find flight
from$160 |
|
10:54 — 13:07
+1 day
|
10:54 — 12:21
G42969
Allegiant Air
Louisville — Myrtle Beach
8h 3m stop
20:24 — 21:50
NK2089
Spirit Airlines
Myrtle Beach — Orlando
14h 2m stop
11:52 — 13:07
MX162
Mexicana
Orlando — Key West
|
26h 13m including layover |
Find flight
from$215 |
|
11:04 — 15:08
+1 day
|
11:04 — 12:22
NK2795
Spirit Airlines
Louisville — Detroit
2h 4m stop
14:26 — 17:08
NK2739
Spirit Airlines
Detroit — Clearwater
20h 57m stop
14:05 — 15:08
G41034
Allegiant Air
Clearwater — Key West
|
28h 4m including layover |
Find flight
from$143 |
|
11:34 — 16:36
+1 day
|
11:34 — 13:49
G41451
Allegiant Air
Louisville — Punta Gorda
7h 22m stop
21:11 — 23:36
G42750
Allegiant Air
Punta Gorda — Pittsburgh
14h 18m stop
13:54 — 16:36
G4991
Allegiant Air
Pittsburgh — Key West
|
29h 2m including layover |
Find flight
from$150 |
|
12:32 — 16:36
+1 day
|
12:32 — 14:54
NK1785
Spirit Airlines
Louisville — Newark
7h 11m stop
22:05 — 23:29
NK1788
Spirit Airlines
Newark — Pittsburgh
14h 25m stop
13:54 — 16:36
G41055
Allegiant Air
Pittsburgh — Key West
|
28h 4m including layover |
Find flight
from$168 |
|
12:34 — 15:26
+1 day
|
12:34 — 13:15
G43102
Allegiant Air
Louisville — Fort Walton Beach
6h 59m stop
20:14 — 22:44
G4256
Allegiant Air
Fort Walton Beach — Fletcher
14h 43m stop
13:27 — 15:26
G4975
Allegiant Air
Fletcher — Key West
|
26h 52m including layover |
Find flight
from$201 |
|
13:35 — 09:43
+1 day
|
13:35 — 15:09
NK2751
Spirit Airlines
Louisville — Myrtle Beach
5h 15m stop
20:24 — 21:50
NK2089
Spirit Airlines
Myrtle Beach — Sanford
10h 42m stop
08:32 — 09:43
G42877
Allegiant Air
Sanford — Key West
|
20h 8m including layover |
Find flight
from$140 |
|
13:35 — 16:45
+1 day
|
13:35 — 15:09
NK2751
Spirit Airlines
Louisville — Myrtle Beach
6h 42m stop
21:51 — 23:36
G4631
Allegiant Air
Myrtle Beach — Indianapolis
14h 28m stop
14:04 — 16:45
G41285
Allegiant Air
Indianapolis — Key West
|
27h 10m including layover |
Find flight
from$175 |
|
14:30 — 13:07
+1 day
|
14:30 — 15:54
NK2051
Spirit Airlines
Louisville — Dallas
4h 35m stop
20:29 — 00:15
NK2263
Spirit Airlines
Dallas — Orlando
11h 37m stop
11:52 — 13:07
MX162
Mexicana
Orlando — Key West
|
22h 37m including layover |
Find flight
from$236 |
|
17:43 — 15:16
+1 day
|
17:43 — 18:24
G41490
Allegiant Air
Louisville — Fort Walton Beach
12h 51m stop
07:15 — 10:10
G43069
Allegiant Air
Fort Walton Beach — Covington
2h 33m stop
12:43 — 15:16
G4426
Allegiant Air
Covington — Key West
|
21h 33m including layover |
Find flight
from$192 |
|
18:04 — 18:42
+1 day
|
18:04 — 20:19
G42482
Allegiant Air
Louisville — Punta Gorda
16h 15m stop
12:34 — 14:19
G41840
Allegiant Air
Punta Gorda — Fletcher
2h 24m stop
16:43 — 18:42
G4228
Allegiant Air
Fletcher — Key West
|
24h 38m including layover |
Find flight
from$155 |
|
20:35 — 16:51
+1 day
|
20:35 — 21:16
G41495
Allegiant Air
Louisville — Fort Walton Beach
9h 14m stop
06:30 — 09:38
G43116
Allegiant Air
Fort Walton Beach — Pittsburgh
4h 31m stop
14:09 — 16:51
G4991
Allegiant Air
Pittsburgh — Key West
|
20h 16m including layover |
Find flight
from$249 |
|
20:35 — 09:22
+2 days
|
20:35 — 22:11
MX229
Mexicana
Louisville — Charleston
16h 37m stop
14:48 — 16:16
MX101
Mexicana
Charleston — Tampa
15h 59m stop
08:15 — 09:22
MX160
Mexicana
Tampa — Key West
|
36h 47m including layover |
Find flight
from$299 |
Flight Information
Below we will explain in detail what the flights cost on the destination from Louisville to Key West depends on and how to choose the most interesting flight option for you.
Distance between Louisville and Key West is 1560 miles. Time difference between the cities is 0h. Airplanes depart 05:03 to 20:35 from 3 Louisville airports and arrive 05:03 to 20:35 to 2 Key West airports. Average flight time is 23h 53m.
- The fastest flight 6h 11m
- Average flight time 23h 53m
- The earliest flight 05:03
- The latest flight 20:35
- Distance 970 ml
The cheapest months to travel to Key West are august (from 86 $), july (from 95 $), september (from 155 $).
The most expensive months are october (from 239 $), september (from 155 $), july (from 95 $).
What is the lowest airfare Louisville to Key West?
The cheapest plane ticket found by our users is $86. This airfare is for economy class on one-way G41099 flight by Allegiant Air for August 8, 2025 which leaves Standiford Field in Louisville at 15:47 am and arrives at Key West Key West Int. at 14:44.
Popular Airlines on the Route
The flight Louisville — Key West is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Mexicana - 8 departures per week at the price of from $ 120 . And the most expensive tickets are offered by United Airlines airline - from $ 724.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 59 flights with layovers on the route. The fastest connecting flight is UA3594 by United Airlines takes 6h 11m and the cheapest is G41099 by Allegiant Air for $86.
- MX - Mexicanafrom $120Find
- UA - United Airlinesfrom $239Find
- G4 - Allegiant Airfrom $86Find
- NK - Spirit Airlinesfrom $102Find
Airports
You can fly from Louisville to Key West from 3 airports (Standiford Field, Intercontinental, Bowman Field).
Louisville airports
- Standiford Field-SDFfrom $86Find
- Intercontinental-LJCFind
- Bowman Field-LOUFind
Key West airports
- NAS-NQXFind
- Key West Int.-EYWFind
Airplanes
There are flights to Key West from Louisville by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Louisville
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Top International Destinations from Louisville
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $56Find
How to book a plane ticket yourself?

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