Cheap Flights from Detroit, MI to San Antonio, TX from $68

Return flight: San Antonio – Detroit
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On Cheapflightsplus.com you will find 2 direct and 433 connecting flights from Detroit to San Antonio. You can compare airfare deals from 6 airlines and multiple travel sites from $68, book and save on cheap plane tickets and last minute offers. Also check out DTT-SAT flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Detroit to San Antonio Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $68 (one-way), $117 (round-trip).
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Best Flights from Detroit to San Antonio Today

Take a look at the list of non stop flights and flights with layovers from Detroit to San Antonio with the lowest price of $68. The fastest direct flight takes 3h 4m and the fastest connecting – 5h 13m.
Price Departure Arrival Flight Duration Airline Flight
from $68
Find flight
19:37
Detroit
All airports
 21:50
San Antonio
San Antonio
 3h 13m Spirit Airlines
NK2746
from $70
Find flight
06:38
Detroit
All airports
 12:32
San Antonio
San Antonio
 6h 54m
layover
2h 28m - Atlanta
 Spirit Airlines
NK2350
NK2171
from $82
Find flight
22:04
Detroit
All airports
 11:37+1 день
San Antonio
San Antonio
 14h 33m
layover
9h 53m - Atlanta
 Spirit Airlines
NK2493
NK2171
from $101
Find flight
21:16
Detroit
All airports
 11:37+1 день
San Antonio
San Antonio
 15h 21m
layover
7h 9m - Orlando
1h 22m - Atlanta
 Spirit Airlines
NK2456
NK2457
NK2171
from $118
Find flight
15:34
Detroit
All airports
 11:14+1 день
San Antonio
San Antonio
 20h 40m
layover
3h 40m - Philadelphia
10h 52m - Atlanta
 Spirit Airlines
NK1013
NK3153
NK1196
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 16, 2025
Full flight schedule will help you in detecting at what time planes fly from Detroit to San Antonio. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:45 — 11:14
05:45 — 07:45 NK1205 Spirit Airlines
Detroit — Atlanta
2h 9m stop
09:54 — 11:14 NK1196 Spirit Airlines
Atlanta — San Antonio
6h 29m
including layover
Find flight
from$91
05:45 — 11:24
05:45 — 08:25 NK1235 Spirit Airlines
Detroit — Tampa
1h 5m stop
09:30 — 11:24 NK1239 Spirit Airlines
Tampa — San Antonio
6h 39m
including layover
Find flight
from$100
06:00 — 08:04
06:00 — 08:04 NK1191 Spirit Airlines
Detroit — San Antonio
3h 4m
Find flight
from$69
06:38 — 12:32
06:38 — 08:36 NK2350 Spirit Airlines
Detroit — Atlanta
2h 28m stop
11:04 — 12:32 NK2171 Spirit Airlines
Atlanta — San Antonio
6h 54m
including layover
Find flight
from$70
07:58 — 16:33
07:58 — 08:39 NK1547 Spirit Airlines
Detroit — Nashville
5h 42m stop
14:21 — 16:33 NK1875 Spirit Airlines
Nashville — San Antonio
9h 35m
including layover
Find flight
from$98
09:47 — 12:32
+1 day
09:47 — 12:25 NK2318 Spirit Airlines
Detroit — Tampa
4h 39m stop
17:04 — 18:40 NK2469 Spirit Airlines
Tampa — Atlanta
16h 24m stop
11:04 — 12:32 NK2171 Spirit Airlines
Atlanta — San Antonio
27h 45m
including layover
Find flight
from$101
09:48 — 11:37
+1 day
09:45 — 11:25 NK2269 Spirit Airlines
Detroit — Philadelphia
55m stop
12:23 — 14:31 NK2270 Spirit Airlines
Philadelphia — Atlanta
19h 38m stop
11:04 — 12:32 NK2171 Spirit Airlines
Atlanta — San Antonio
26h 49m
including layover
Find flight
from$101
11:38 — 11:14
+1 day
11:38 — 13:38 NK1024 Spirit Airlines
Detroit — Atlanta
20h 16m stop
09:54 — 11:14 NK1196 Spirit Airlines
Atlanta — San Antonio
24h 36m
including layover
Find flight
from$91
12:22 — 11:14
+1 day
12:22 — 14:22 NK1104 Spirit Airlines
Detroit — Atlanta
19h 32m stop
09:54 — 11:14 NK1196 Spirit Airlines
Atlanta — San Antonio
23h 52m
including layover
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from$91
13:43 — 12:32
+1 day
13:43 — 15:41 NK2215 Spirit Airlines
Detroit — Atlanta
19h 23m stop
11:04 — 12:32 NK2171 Spirit Airlines
Atlanta — San Antonio
23h 49m
including layover
Find flight
from$82
14:50 — 11:14
+1 day
14:50 — 16:51 NK1159 Spirit Airlines
Detroit — Atlanta
17h 3m stop
09:54 — 11:14 NK1196 Spirit Airlines
Atlanta — San Antonio
21h 24m
including layover
Find flight
from$91
19:37 — 21:50
19:37 — 21:50 NK2746 Spirit Airlines
Detroit — San Antonio
3h 13m
Find flight
from$68
19:59 — 10:47
+1 day
19:59 — 21:24 NK2143 Spirit Airlines
Detroit — Las Vegas
8h 46m stop
06:10 — 10:47 NK2180 Spirit Airlines
Las Vegas — San Antonio
15h 48m
including layover
Find flight
from$78
20:20 — 05:00
+1 day
19:59 — 21:24 NK2143 Spirit Airlines
Detroit — Las Vegas
2h 41m stop
00:33 — 05:04 NK2705 Spirit Airlines
Las Vegas — San Antonio
9h 40m
including layover
Find flight
from$78
22:04 — 11:37
+1 day
21:09 — 23:11 NK2493 Spirit Airlines
Detroit — Atlanta
9h 53m stop
11:04 — 12:32 NK2171 Spirit Airlines
Atlanta — San Antonio
14h 33m
including layover
Find flight
from$82
*Departure and arrival times - local. Updated on September 16, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Detroit to San Antonio depends on and how to choose the most interesting flight option for you.

Distance between Detroit and San Antonio is 1983 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 22:33 from 2 Detroit airports and arrive 05:00 to 22:33 to 5 San Antonio airports. Average flight time is 3h 9m.

  • The fastest flight 3h 4m
  • Average flight time 3h 9m
  • The earliest flight 05:00
  • The latest flight 22:33
  • Distance 1233 ml

The cheapest months to travel to San Antonio are june (from 68 $), july (from 69 $), may (from 70 $).

The most expensive months are october (from 123 $), august (from 92 $), september (from 91 $).

What is the lowest airfare Detroit to San Antonio?

The cheapest plane ticket found by our users is $68. This airfare is for economy class on one-way NK2746 flight by Spirit Airlines for June 6, 2025 which leaves All airports in Detroit at 19:37 am and arrives at San Antonio San Antonio at 21:50.

Economy class
$68
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Business class
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First class
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Popular Airlines on the Route

The flight Detroit — San Antonio is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 17 departures per week at the price of from $ 276 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 805.

Direct flights

There are 2 nonstop flights on the route. The fastest direct flight is NK1191 by Spirit Airlines takes 3h 4m and the cheapest is NK2746 by Spirit Airlines for $68.

  • NK - Spirit Airlines
    from $68
    Find
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Connecting Flights

There are 433 flights with layovers on the route. The fastest connecting flight is UA6251 by United Airlines takes 5h 13m and the cheapest is NK2746 by Spirit Airlines for $70.

  • AS - Alaska Airlines
    from $276
    Find
  • F9 - Frontier Airlines
    from $107
    Find
  • SY - Sun Country Airlines
    from $144
    Find
  • HA - Hawaiian Airlines
    from $371
    Find
  • UA - United Airlines
    from $257
    Find
  • NK - Spirit Airlines
    from $70
    Find
See more connecting flights

Airports

You can fly from Detroit to San Antonio from 2 airports (Willow Run, Detroit City).

Detroit airports

  • Willow Run-YIP
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  • Detroit City-DET
    Find

San Antonio airports

  • Randolph AFB-RND
    Find
  • Martindale AAF-MDA
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  • San Antonio-SAT
    Find
  • Kelly AFB-SKF
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  • Stinson Municipal-SSF
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Airplanes

There are flights to San Antonio from Detroit by 6 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Detroit

You may also consider searching for discounted plane tickets to some other popular places from Detroit within United States.

Top International Destinations from Detroit

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
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  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

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