Cheap Flights from Detroit, MI to Key West, FL from $115

On Cheapflightsplus.com you will find 235 connecting flights from Detroit to Key West. You can compare airfare deals from 3 airlines and multiple travel sites from $115, book and save on cheap plane tickets and last minute offers. Also check out DTT-EYW flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Detroit to Key West depends on and how to choose the most interesting flight option for you.

Distance between Detroit and Key West is 1980 miles. Time difference between the cities is 0h. Airplanes depart 05:00 to 22:04 from 2 Detroit airports and arrive 05:00 to 22:04 to 2 Key West airports. Average flight time is 24h 1m.

  • The fastest flight 7h 42m
  • Average flight time 24h 1m
  • The earliest flight 05:00
  • The latest flight 22:04
  • Distance 1231 ml

The cheapest months to travel to Key West are june (from 115 $), july (from 119 $), may (from 127 $).

The most expensive months are september (from 208 $), august (from 154 $), october (from 133 $).

What is the lowest airfare Detroit to Key West?

The cheapest plane ticket found by our users is $115. This airfare is for economy class on one-way NK2739 flight by Spirit Airlines for July 6, 2025 which leaves All airports in Detroit at 14:26 am and arrives at Key West Key West Int. at 09:33.

Economy class
$115
Find
Business class
?
Find
First class
?
Find

Flight Schedule Detroit (Michigan) to Key West (Florida)

05:42 — 15:03+1day
33h 21m flight time
Find flight
from$149
05:42 — 07:10 Detroit — Baltimore
NK2664 Spirit Airlines
11h 25m stop
18:35 — 21:05 Baltimore — Clearwater
NK2447 Spirit Airlines
16h 55m stop
14:00 — 15:03 Clearwater — Key West
G41071 Allegiant Air
06:38 — 15:03+1day
32h 25m flight time
Find flight
from$149
06:38 — 08:36 Detroit — Atlanta
NK2350 Spirit Airlines
6h 9m stop
14:45 — 16:08 Atlanta — Clearwater
NK2468 Spirit Airlines
21h 52m stop
14:00 — 15:03 Clearwater — Key West
G41071 Allegiant Air
07:30 — 09:43+1day
26h 13m flight time
Find flight
from$125
07:30 — 10:13 Detroit — Sanford
NK2456 Spirit Airlines
22h 19m stop
08:32 — 09:43 Sanford — Key West
G42877 Allegiant Air
07:30 — 09:42+1day
26h 12m flight time
Find flight
from$147
07:30 — 10:13 Detroit — Sanford
NK2456 Spirit Airlines
22h 17m stop
08:30 — 09:42 Sanford — Key West
G42861 Allegiant Air
08:55 — 15:03+1day
30h 8m flight time
Find flight
from$149
08:55 — 10:47 Detroit — Charlotte
NK2489 Spirit Airlines
4h 6m stop
14:53 — 16:37 Charlotte — Clearwater
NK2490 Spirit Airlines
21h 23m stop
14:00 — 15:03 Clearwater — Key West
G41071 Allegiant Air
09:04 — 09:12+1day
24h 8m flight time
Find flight
from$133
09:04 — 11:41 Detroit — Clearwater
NK2384 Spirit Airlines
20h 29m stop
08:10 — 09:12 Clearwater — Key West
G4973 Allegiant Air
09:07 — 16:36+1day
31h 29m flight time
Find flight
from$149
09:07 — 10:48 Detroit — Newark
NK1415 Spirit Airlines
11h 17m stop
22:05 — 23:29 Newark — Pittsburgh
NK1788 Spirit Airlines
14h 25m stop
13:54 — 16:36 Pittsburgh — Key West
G4991 Allegiant Air
09:47 — 09:33+1day
23h 46m flight time
Find flight
from$139
09:47 — 12:25 Detroit — Clearwater
NK2318 Spirit Airlines
20h 5m stop
08:30 — 09:33 Clearwater — Key West
G4971 Allegiant Air
12:20 — 08:03+1day
19h 43m flight time
Find flight
from$142
12:20 — 15:17 Detroit — Miami
NK2743 Spirit Airlines
3h 58m stop
19:15 — 20:17 Miami — Clearwater
NK2233 Spirit Airlines
10h 43m stop
07:00 — 08:03 Clearwater — Key West
G4971 Allegiant Air
14:26 — 09:33+1day
19h 7m flight time
Find flight
from$115
09:44 — 12:26 Detroit — Clearwater
NK2739 Spirit Airlines
15h 22m stop
07:00 — 08:03 Clearwater — Key West
G4971 Allegiant Air
14:26 — 15:08+1day
24h 42m flight time
Find flight
from$119
14:26 — 17:08 Detroit — Clearwater
NK2739 Spirit Airlines
20h 57m stop
14:05 — 15:08 Clearwater — Key West
G41034 Allegiant Air
15:32 — 09:42+1day
18h 10m flight time
Find flight
from$147
15:32 — 18:19 Detroit — Sanford
NK2109 Spirit Airlines
14h 11m stop
08:30 — 09:42 Sanford — Key West
G42861 Allegiant Air
18:56 — 09:12+1day
14h 16m flight time
Find flight
from$133
18:56 — 21:31 Detroit — Clearwater
NK2083 Spirit Airlines
10h 39m stop
08:10 — 09:12 Clearwater — Key West
G4973 Allegiant Air
20:40 — 15:03+1day
18h 23m flight time
Find flight
from$116
20:40 — 23:15 Detroit — Clearwater
NK2676 Spirit Airlines
14h 45m stop
14:00 — 15:03 Clearwater — Key West
G41071 Allegiant Air
21:56 — 08:03+1day
10h 7m flight time
Find flight
from$115
20:40 — 23:15 Detroit — Clearwater
NK2676 Spirit Airlines
6h 21m stop
07:00 — 08:03 Clearwater — Key West
G4971 Allegiant Air
Full flight schedule will help you in detecting at what time planes fly from Detroit to Key West. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on November 8, 2025.

Popular Airlines on the Route

The flight Detroit — Key West is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Sun Country Airlines - 1 departures per week at the price of from $ 340 . And the most expensive tickets are offered by United Airlines airline - from $ 668.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 235 flights with layovers on the route. The fastest connecting flight is NK2664 by Spirit Airlines takes 7h 42m and the cheapest is NK2739 by Spirit Airlines for $115.

  • SY - Sun Country Airlines
    from $340
    Find
  • UA - United Airlines
    from $246
    Find
  • NK - Spirit Airlines
    from $115
    Find
See more connecting flights

Airports

You can fly from Detroit to Key West from 2 airports (Willow Run, Detroit City).

Detroit airports

  • Willow Run-YIP
    Find
  • Detroit City-DET
    Find

Key West airports

  • NAS-NQX
    Find
  • Key West Int.-EYW
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back