Cheap Flights from Detroit, MI to Key West, FL from $112

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On Cheapflightsplus.com you will find 235 connecting flights from Detroit to Key West. You can compare airfare deals from 3 airlines and multiple travel sites from $112, book and save on cheap plane tickets and last minute offers. Also check out DTT-EYW flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Detroit to Key West Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $112 (one-way), $192 (round-trip).
Direct flights
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Best Flights from Detroit to Key West Today

Take a look at the list of non stop flights and flights with layovers from Detroit to Key West with the lowest price of $112. Take a look at the list of flights with layovers from Detroit to Key West from $112. There’re no direct flights. The fastest connecting flight – 7h 42m.
Price Departure Arrival Flight Duration Airline Flight
from $112
Find flight
21:56
Detroit
All airports
 08:03+1 день
Key West
Key West Int.
 10h 7m
layover
6h 21m - Clearwater
 Spirit Airlines
NK2676
G4971
from $130
Find flight
18:56
Detroit
All airports
 09:12+1 день
Key West
Key West Int.
 14h 16m
layover
10h 39m - Clearwater
 Spirit Airlines
NK2083
G4973
from $139
Find flight
12:20
Detroit
All airports
 08:03+1 день
Key West
Key West Int.
 19h 43m
layover
3h 58m - Miami
10h 43m - Clearwater
 Spirit Airlines
NK2743
NK2233
G4971
from $160
Find flight
12:25
Detroit
All airports
 15:08+1 день
Key West
Key West Int.
 26h 43m
layover
2h 15m - Louisville
20h 13m - Clearwater
 Spirit Airlines
NK1255
G41099
G41034
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 19, 2025
Full flight schedule will help you in detecting at what time planes fly from Detroit to Key West. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:42 — 15:03
+1 day
05:42 — 07:10 NK2664 Spirit Airlines
Detroit — Baltimore
11h 25m stop
18:35 — 21:05 NK2447 Spirit Airlines
Baltimore — Clearwater
16h 55m stop
14:00 — 15:03 G41071 Allegiant Air
Clearwater — Key West
33h 21m
including layover
Find flight
from$146
06:38 — 15:03
+1 day
06:38 — 08:36 NK2350 Spirit Airlines
Detroit — Atlanta
6h 9m stop
14:45 — 16:08 NK2468 Spirit Airlines
Atlanta — Clearwater
21h 52m stop
14:00 — 15:03 G41071 Allegiant Air
Clearwater — Key West
32h 25m
including layover
Find flight
from$146
07:30 — 09:43
+1 day
07:30 — 10:13 NK2456 Spirit Airlines
Detroit — Sanford
22h 19m stop
08:32 — 09:43 G42877 Allegiant Air
Sanford — Key West
26h 13m
including layover
Find flight
from$122
07:30 — 09:42
+1 day
07:30 — 10:13 NK2456 Spirit Airlines
Detroit — Sanford
22h 17m stop
08:30 — 09:42 G42861 Allegiant Air
Sanford — Key West
26h 12m
including layover
Find flight
from$144
08:55 — 15:03
+1 day
08:55 — 10:47 NK2489 Spirit Airlines
Detroit — Charlotte
4h 6m stop
14:53 — 16:37 NK2490 Spirit Airlines
Charlotte — Clearwater
21h 23m stop
14:00 — 15:03 G41071 Allegiant Air
Clearwater — Key West
30h 8m
including layover
Find flight
from$146
09:04 — 09:12
+1 day
09:04 — 11:41 NK2384 Spirit Airlines
Detroit — Clearwater
20h 29m stop
08:10 — 09:12 G4973 Allegiant Air
Clearwater — Key West
24h 8m
including layover
Find flight
from$130
09:07 — 16:36
+1 day
09:07 — 10:48 NK1415 Spirit Airlines
Detroit — Newark
11h 17m stop
22:05 — 23:29 NK1788 Spirit Airlines
Newark — Pittsburgh
14h 25m stop
13:54 — 16:36 G4991 Allegiant Air
Pittsburgh — Key West
31h 29m
including layover
Find flight
from$146
09:47 — 09:33
+1 day
09:47 — 12:25 NK2318 Spirit Airlines
Detroit — Clearwater
20h 5m stop
08:30 — 09:33 G4971 Allegiant Air
Clearwater — Key West
23h 46m
including layover
Find flight
from$136
12:20 — 08:03
+1 day
12:20 — 15:17 NK2743 Spirit Airlines
Detroit — Miami
3h 58m stop
19:15 — 20:17 NK2233 Spirit Airlines
Miami — Clearwater
10h 43m stop
07:00 — 08:03 G4971 Allegiant Air
Clearwater — Key West
19h 43m
including layover
Find flight
from$139
14:26 — 09:33
+1 day
09:44 — 12:26 NK2739 Spirit Airlines
Detroit — Clearwater
15h 22m stop
07:00 — 08:03 G4971 Allegiant Air
Clearwater — Key West
19h 7m
including layover
Find flight
from$112
14:26 — 15:08
+1 day
14:26 — 17:08 NK2739 Spirit Airlines
Detroit — Clearwater
20h 57m stop
14:05 — 15:08 G41034 Allegiant Air
Clearwater — Key West
24h 42m
including layover
Find flight
from$116
15:32 — 09:42
+1 day
15:32 — 18:19 NK2109 Spirit Airlines
Detroit — Sanford
14h 11m stop
08:30 — 09:42 G42861 Allegiant Air
Sanford — Key West
18h 10m
including layover
Find flight
from$144
18:56 — 09:12
+1 day
18:56 — 21:31 NK2083 Spirit Airlines
Detroit — Clearwater
10h 39m stop
08:10 — 09:12 G4973 Allegiant Air
Clearwater — Key West
14h 16m
including layover
Find flight
from$130
20:40 — 15:03
+1 day
20:40 — 23:15 NK2676 Spirit Airlines
Detroit — Clearwater
14h 45m stop
14:00 — 15:03 G41071 Allegiant Air
Clearwater — Key West
18h 23m
including layover
Find flight
from$114
21:56 — 08:03
+1 day
20:40 — 23:15 NK2676 Spirit Airlines
Detroit — Clearwater
6h 21m stop
07:00 — 08:03 G4971 Allegiant Air
Clearwater — Key West
10h 7m
including layover
Find flight
from$112
*Departure and arrival times - local. Updated on September 19, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Detroit to Key West depends on and how to choose the most interesting flight option for you.

Distance between Detroit and Key West is 1980 miles. Time difference between the cities is 0h. Airplanes depart 05:00 to 22:04 from 2 Detroit airports and arrive 05:00 to 22:04 to 2 Key West airports. Average flight time is 24h 1m.

  • The fastest flight 7h 42m
  • Average flight time 24h 1m
  • The earliest flight 05:00
  • The latest flight 22:04
  • Distance 1231 ml

The cheapest months to travel to Key West are june (from 112 $), july (from 116 $), may (from 124 $).

The most expensive months are september (from 203 $), august (from 150 $), october (from 130 $).

What is the lowest airfare Detroit to Key West?

The cheapest plane ticket found by our users is $112. This airfare is for economy class on one-way NK2739 flight by Spirit Airlines for July 6, 2025 which leaves All airports in Detroit at 14:26 am and arrives at Key West Key West Int. at 09:33.

Economy class
$112
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Business class
?
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First class
?
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Popular Airlines on the Route

The flight Detroit — Key West is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Sun Country Airlines - 1 departures per week at the price of from $ 333 . And the most expensive tickets are offered by United Airlines airline - from $ 653.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 235 flights with layovers on the route. The fastest connecting flight is NK2664 by Spirit Airlines takes 7h 42m and the cheapest is NK2739 by Spirit Airlines for $112.

  • SY - Sun Country Airlines
    from $333
    Find
  • UA - United Airlines
    from $241
    Find
  • NK - Spirit Airlines
    from $112
    Find
See more connecting flights

Airports

You can fly from Detroit to Key West from 2 airports (Willow Run, Detroit City).

Detroit airports

  • Willow Run-YIP
    Find
  • Detroit City-DET
    Find

Key West airports

  • NAS-NQX
    Find
  • Key West Int.-EYW
    Find

Airplanes

There are flights to Key West from Detroit by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Detroit

You may also consider searching for discounted plane tickets to some other popular places from Detroit within United States.

Top International Destinations from Detroit

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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