Cheap Flights from Denver, CO to Knoxville, TN from $155

Return flight: Knoxville – Denver
Page navigation
Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 36 connecting flights from Denver to Knoxville. You can compare airfare deals from 3 airlines and multiple travel sites from $155, book and save on cheap plane tickets and last minute offers. Also check out DEN-TYS flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Denver to Knoxville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $155 (one-way), $266 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights

Best Flights from Denver to Knoxville Today

Take a look at the list of non stop flights and flights with layovers from Denver to Knoxville with the lowest price of $155. Take a look at the list of flights with layovers from Denver to Knoxville from $155. There’re no direct flights. The fastest connecting flight – 5h 47m.
Price Departure Arrival Flight Duration Airline Flight
from $300
Find flight
23:59
Denver
Denver International
 10:27+1 день
Knoxville
Mc Ghee Tyson
 8h 28m
layover
3h 21m - Washington D.C.
 United Airlines
UA1924
UA4257
from $362
Find flight
20:55
Denver
Denver International
 13:21+1 день
Knoxville
Mc Ghee Tyson
 14h 26m
layover
10h 5m - Chicago
 United Airlines
UA377
UA5836
from $155
Find flight
18:44
Denver
Denver International
 21:42+1 день
Knoxville
Mc Ghee Tyson
 24h 58m
layover
14h 31m - Fletcher
4h 42m - Fort Walton Beach
 Allegiant Air
G4226
G4263
G41396
from $185
Find flight
08:00
Denver
Denver International
 21:40+1 день
Knoxville
Mc Ghee Tyson
 35h 40m
layover
22h 46m - Covington
6h 22m - Clearwater
 Allegiant Air
G4411
G42042
G43048
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 15, 2025
Full flight schedule will help you in detecting at what time planes fly from Denver to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
08:00 — 21:40
+1 day
08:00 — 12:42 G4411 Allegiant Air
Denver — Covington
22h 46m stop
11:28 — 13:38 G42042 Allegiant Air
Covington — Clearwater
6h 22m stop
20:00 — 21:40 G43048 Allegiant Air
Clearwater — Knoxville
35h 40m
including layover
Find flight
from$185
08:00 — 21:42
+1 day
08:00 — 12:42 G4411 Allegiant Air
Denver — Covington
19h 48m stop
08:30 — 09:20 G4363 Allegiant Air
Covington — Fort Walton Beach
10h 1m stop
19:21 — 21:42 G41396 Allegiant Air
Fort Walton Beach — Knoxville
35h 42m
including layover
Find flight
from$213
08:00 — 16:39
+1 day
08:00 — 12:42 G4411 Allegiant Air
Denver — Covington
19h 48m stop
08:30 — 09:20 G4363 Allegiant Air
Covington — Fort Walton Beach
4h 58m stop
14:18 — 16:39 G43043 Allegiant Air
Fort Walton Beach — Knoxville
30h 39m
including layover
Find flight
from$296
10:07 — 23:27
10:07 — 13:38 UA2676 United Airlines
Denver — Houston
6h 22m stop
20:12 — 23:39 UA4810 United Airlines
Houston — Knoxville
11h 20m
including layover
Find flight
from$471
14:44 — 10:17
+1 day
14:44 — 18:24 UA1023 United Airlines
Denver — Chicago
13h 1m stop
07:25 — 10:17 UA5726 United Airlines
Chicago — Knoxville
17h 33m
including layover
Find flight
from$367
18:13 — 22:47
+1 day
18:13 — 21:14 SY658 Sun Country Airlines
Denver — Minneapolis
10h 22m stop
07:36 — 11:49 SY341 Sun Country Airlines
Minneapolis — Sanford
9h 23m stop
21:12 — 22:47 G43054 Allegiant Air
Sanford — Knoxville
26h 34m
including layover
Find flight
from$453
18:44 — 21:42
+1 day
16:05 — 21:00 G4226 Allegiant Air
Denver — Fletcher
14h 31m stop
14:10 — 14:39 G4263 Allegiant Air
Fletcher — Fort Walton Beach
4h 42m stop
19:21 — 21:42 G41396 Allegiant Air
Fort Walton Beach — Knoxville
24h 58m
including layover
Find flight
from$155
18:44 — 22:47
+1 day
16:05 — 21:00 G4226 Allegiant Air
Denver — Fletcher
18h 10m stop
17:49 — 19:18 G4231 Allegiant Air
Fletcher — Sanford
1h 54m stop
21:12 — 22:47 G43054 Allegiant Air
Sanford — Knoxville
26h 3m
including layover
Find flight
from$160
18:44 — 22:47
+1 day
16:05 — 21:00 G4226 Allegiant Air
Denver — Fletcher
13h 57m stop
13:36 — 15:05 G41891 Allegiant Air
Fletcher — Sanford
6h 7m stop
21:12 — 22:47 G43054 Allegiant Air
Sanford — Knoxville
26h 3m
including layover
Find flight
from$166
18:44 — 21:40
+1 day
16:05 — 21:00 G4226 Allegiant Air
Denver — Fletcher
12h 6m stop
11:45 — 13:23 G41879 Allegiant Air
Fletcher — Clearwater
6h 37m stop
20:00 — 21:40 G43048 Allegiant Air
Clearwater — Knoxville
24h 56m
including layover
Find flight
from$194
18:44 — 17:59
+1 day
16:05 — 21:00 G4226 Allegiant Air
Denver — Fletcher
13h 57m stop
13:36 — 15:05 G41891 Allegiant Air
Fletcher — Sanford
1h 19m stop
16:24 — 17:59 G43059 Allegiant Air
Sanford — Knoxville
21h 15m
including layover
Find flight
from$205
20:55 — 13:21
+1 day
20:50 — 00:25 UA377 United Airlines
Denver — Chicago
10h 5m stop
10:35 — 13:21 UA5836 United Airlines
Chicago — Knoxville
14h 26m
including layover
Find flight
from$362
20:55 — 17:05
+1 day
20:55 — 00:30 UA377 United Airlines
Denver — Chicago
13h 38m stop
14:08 — 17:05 UA5429 United Airlines
Chicago — Knoxville
18h 10m
including layover
Find flight
from$382
20:55 — 22:35
+1 day
20:50 — 00:25 UA377 United Airlines
Denver — Chicago
19h 20m stop
19:55 — 22:40 UA2005 United Airlines
Chicago — Knoxville
23h 40m
including layover
Find flight
from$382
23:59 — 10:27
+1 day
23:50 — 05:15 UA1924 United Airlines
Denver — Washington D.C.
3h 21m stop
08:45 — 10:27 UA4257 United Airlines
Washington D.C. — Knoxville
8h 28m
including layover
Find flight
from$300
*Departure and arrival times - local. Updated on September 15, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Denver to Knoxville depends on and how to choose the most interesting flight option for you.

Distance between Denver and Knoxville is 1866 miles. Time difference between the cities is 2h. Airplanes depart 06:01 to 23:59 from 2 Denver airports and arrive 06:01 to 23:59 to 1 Knoxville airport. Average flight time is 16h 43m.

  • The fastest flight 5h 47m
  • Average flight time 16h 43m
  • The earliest flight 06:01
  • The latest flight 23:59
  • Distance 1160 ml

The cheapest months to travel to Knoxville are july (from 155 $), august (from 213 $), june (from 300 $).

The most expensive months are may (from 329 $), june (from 300 $), august (from 213 $).

What is the lowest airfare Denver to Knoxville?

The cheapest plane ticket found by our users is $155. This airfare is for economy class on one-way G4226 flight by Allegiant Air for August 1, 2025 which leaves Denver International in Denver at 18:44 am and arrives at Knoxville Mc Ghee Tyson at 21:42.

Economy class
$155
Find
Business class
?
Find
First class
?
Find

Popular Airlines on the Route

The flight Denver — Knoxville is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Sun Country Airlines - 3 departures per week at the price of from $ 453 . And the most expensive tickets are offered by United Airlines airline - from $ 1560.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 36 flights with layovers on the route. The fastest connecting flight is UA489 by United Airlines takes 5h 47m and the cheapest is G4226 by Allegiant Air for $155.

  • SY - Sun Country Airlines
    from $453
    Find
  • UA - United Airlines
    from $300
    Find
  • G4 - Allegiant Air
    from $155
    Find
See more connecting flights

Airports

You can fly from Denver to Knoxville from 2 airports (Denver International, Arapahoe Co).

Denver airports

  • Denver International-DEN
    from $155
    Find
  • Arapahoe Co-APA
    Find

Knoxville airports

  • Mc Ghee Tyson-TYS
    Find

Airplanes

There are flights to Knoxville from Denver by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Denver

You may also consider searching for discounted plane tickets to some other popular places from Denver within United States.

Top International Destinations from Denver

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back