Cheap Flights from Denver, CO to Knoxville, TN from $45
Return flight: Knoxville – Denver
On Cheapflightsplus.com you will find 8 direct and 241 connecting flights from Denver to Knoxville. You can compare airfare deals from 6 airlines and multiple travel sites from $45, book and save on cheap plane tickets and last minute offers. Also check out DEN-TYS flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Denver to Knoxville Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $45 (one-way), $77 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Denver to Knoxville Today
Take a look at the list of non stop flights and flights with layovers from Denver to Knoxville with the lowest price of $45. The fastest direct flight takes 2h 43m and the fastest connecting – 5h 13m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $45 | 17:42 Denver Denver International | 22:27 Knoxville Mc Ghee Tyson | 2h 45m | Allegiant Air | G41422 |
| from $48 | 11:58 Denver Denver International | 16:43 Knoxville Mc Ghee Tyson | 2h 45m | Allegiant Air | G43041 |
| from $76 | 17:42 Denver Denver International | 22:27 Knoxville Mc Ghee Tyson | 2h 45m | Allegiant Air | G41423 |
| from $93 | 17:44 Denver Denver International | 22:27 Knoxville Mc Ghee Tyson | 2h 43m | Allegiant Air | G41438 |
| from $99 | 11:41 Denver Denver International | 16:29 Knoxville Mc Ghee Tyson | 2h 48m | Frontier Airlines | F92374 |
| from $138 | 17:20 Denver Denver International | 22:22 Knoxville Mc Ghee Tyson | 3h 2m | United Airlines | UA4774 |
| from $163 | 10:15 Denver Denver International | 15:04 Knoxville Mc Ghee Tyson | 2h 49m | United Airlines | UA2420 |
| from $192 | 10:25 Denver Denver International | 15:15 Knoxville Mc Ghee Tyson | 2h 50m | United Airlines | UA1631 |
| from $87 | 17:59 Denver Denver International | 16:12+1 день Knoxville Mc Ghee Tyson | 20h 13m layover 16h 9m - Minneapolis | Sun Country Airlines | SY656 G43063 |
| from $111 | 10:20 Denver Denver International | 16:12+1 день Knoxville Mc Ghee Tyson | 27h 52m layover 23h 52m - Minneapolis | Sun Country Airlines | SY652 G43063 |
| from $141 | 18:25 Denver Denver International | 16:12+1 день Knoxville Mc Ghee Tyson | 19h 47m layover 15h 43m - Minneapolis | Sun Country Airlines | SY658 G43062 |
| from $120 | 16:05 Denver Denver International | 15:02+1 день Knoxville Mc Ghee Tyson | 20h 57m layover 11h 0m - Fletcher 3h 5m - Miami | Allegiant Air | G4226 G41847 G4509 |
| from $123 | 08:00 Denver Denver International | 21:40+1 день Knoxville Mc Ghee Tyson | 35h 40m layover 5h 50m - Covington 23h 22m - Clearwater | Allegiant Air | G4411 G4382 G43048 |
| from $124 | 08:00 Denver Denver International | 10:04+1 день Knoxville Mc Ghee Tyson | 24h 4m layover 4h 34m - Covington 12h 18m - Miami | Allegiant Air | G42008 G4397 G4527 |
| from $124 | 16:05 Denver Denver International | 21:42+1 день Knoxville Mc Ghee Tyson | 27h 37m layover 17h 10m - Fletcher 4h 42m - Fort Walton Beach | Allegiant Air | G4226 G4263 G41396 |
| from $125 | 18:44 Denver Denver International | 18:14+1 день Knoxville Mc Ghee Tyson | 21h 30m layover 10h 21m - Fletcher 5h 10m - Sanford | Allegiant Air | G4226 G4270 G43040 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on June 25, 2025
Flight Schedule Denver (Colorado) to Knoxville (Tennessee)
Full flight schedule will help you in detecting at what time planes fly from Denver to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
10:15 — 15:04
|
10:15 — 15:04
UA2420
United Airlines
Denver — Knoxville
|
2h 49m |
Find flight
from$163 |
|
|
10:25 — 15:15
|
10:25 — 15:15
UA1631
United Airlines
Denver — Knoxville
|
2h 50m |
Find flight
from$192 |
|
|
11:41 — 16:29
|
11:41 — 16:29
F92374
Frontier Airlines
Denver — Knoxville
|
2h 48m |
Find flight
from$99 |
|
|
11:58 — 16:43
|
11:58 — 16:43
G43041
Allegiant Air
Denver — Knoxville
|
2h 45m |
Find flight
from$48 |
|
|
17:20 — 22:22
|
17:20 — 22:22
UA4774
United Airlines
Denver — Knoxville
|
3h 2m |
Find flight
from$138 |
|
|
17:42 — 22:27
|
17:42 — 22:27
G41422
Allegiant Air
Denver — Knoxville
|
2h 45m |
Find flight
from$45 |
|
|
17:42 — 22:27
|
17:42 — 22:27
G41423
Allegiant Air
Denver — Knoxville
|
2h 45m |
Find flight
from$76 |
|
|
17:44 — 22:27
|
17:44 — 22:27
G41438
Allegiant Air
Denver — Knoxville
|
2h 43m |
Find flight
from$93 |
|
|
10:15 — 16:12
+1 day
|
10:15 — 13:12
SY652
Sun Country Airlines
Denver — Minneapolis
23h 57m stop
13:09 — 16:12
G43062
Allegiant Air
Minneapolis — Knoxville
|
27h 57m including layover |
Find flight
from$124 |
|
|
10:20 — 16:12
+1 day
|
10:20 — 13:17
SY652
Sun Country Airlines
Denver — Minneapolis
23h 52m stop
13:09 — 16:12
G43063
Allegiant Air
Minneapolis — Knoxville
|
27h 52m including layover |
Find flight
from$111 |
|
|
20:07 — 16:11
+1 day
|
20:07 — 23:08
SY658
Sun Country Airlines
Denver — Minneapolis
14h stop
13:08 — 16:11
G43063
Allegiant Air
Minneapolis — Knoxville
|
18h 4m including layover |
Find flight
from$158 |
|
|
06:15 — 16:47
+1 day
|
06:15 — 09:12
SY1610
Sun Country Airlines
Denver — Minneapolis
23h stop
08:12 — 11:31
SY223
Sun Country Airlines
Minneapolis — Washington D.C.
3h 42m stop
15:13 — 16:47
G41398
Allegiant Air
Washington D.C. — Knoxville
|
32h 32m including layover |
Find flight
from$141 |
|
|
06:15 — 17:18
+1 day
|
06:15 — 09:12
SY1610
Sun Country Airlines
Denver — Minneapolis
8h 24m stop
17:36 — 19:17
SY261
Sun Country Airlines
Minneapolis — Chicago
19h 36m stop
14:53 — 17:18
G43025
Allegiant Air
Chicago — Knoxville
|
33h 3m including layover |
Find flight
from$152 |
|
|
08:00 — 21:40
+1 day
|
08:00 — 12:42
G4411
Allegiant Air
Denver — Covington
5h 50m stop
18:32 — 20:38
G4382
Allegiant Air
Covington — Clearwater
23h 22m stop
20:00 — 21:40
G43048
Allegiant Air
Clearwater — Knoxville
|
35h 40m including layover |
Find flight
from$123 |
|
|
08:00 — 10:04
+1 day
|
08:00 — 12:39
G42008
Allegiant Air
Denver — Covington
4h 34m stop
17:13 — 19:42
G4397
Allegiant Air
Covington — Miami
12h 18m stop
08:00 — 10:04
G4527
Allegiant Air
Miami — Knoxville
|
24h 4m including layover |
Find flight
from$124 |
|
|
09:51 — 15:12
+1 day
|
09:51 — 15:21
G4166
Allegiant Air
Denver — Allentown
5h 55m stop
21:16 — 23:39
G41191
Allegiant Air
Allentown — Sanford
13h 58m stop
13:37 — 15:12
G41411
Allegiant Air
Sanford — Knoxville
|
27h 21m including layover |
Find flight
from$153 |
|
|
09:51 — 19:11
+1 day
|
09:51 — 15:21
G4166
Allegiant Air
Denver — Allentown
5h 55m stop
21:16 — 23:39
G41191
Allegiant Air
Allentown — Sanford
17h 57m stop
17:36 — 19:11
G42962
Allegiant Air
Sanford — Knoxville
|
31h 20m including layover |
Find flight
from$153 |
|
|
13:50 — 14:32
+1 day
|
13:50 — 14:35
LF3317
flynordic
Denver — Page
1h 40m stop
16:15 — 17:30
LF3305
flynordic
Page — Phoenix
14h 35m stop
08:05 — 14:32
G43052
Allegiant Air
Phoenix — Knoxville
|
22h 42m including layover |
Find flight
from$156 |
|
|
16:05 — 15:02
+1 day
|
16:05 — 21:00
G4226
Allegiant Air
Denver — Fletcher
11h stop
08:00 — 09:55
G41847
Allegiant Air
Fletcher — Miami
3h 5m stop
13:00 — 15:02
G4509
Allegiant Air
Miami — Knoxville
|
20h 57m including layover |
Find flight
from$120 |
|
|
16:05 — 21:42
+1 day
|
16:05 — 21:00
G4226
Allegiant Air
Denver — Fletcher
17h 10m stop
14:10 — 14:39
G4263
Allegiant Air
Fletcher — Fort Walton Beach
4h 42m stop
19:21 — 21:42
G41396
Allegiant Air
Fort Walton Beach — Knoxville
|
27h 37m including layover |
Find flight
from$124 |
|
|
18:44 — 18:14
+1 day
|
18:44 — 23:39
G4226
Allegiant Air
Denver — Fletcher
10h 21m stop
10:00 — 11:29
G4270
Allegiant Air
Fletcher — Sanford
5h 10m stop
16:39 — 18:14
G43040
Allegiant Air
Sanford — Knoxville
|
21h 30m including layover |
Find flight
from$125 |
|
|
18:44 — 19:56
+1 day
|
18:44 — 23:39
G4226
Allegiant Air
Denver — Fletcher
11h 12m stop
10:51 — 12:46
G4492
Allegiant Air
Fletcher — Miami
5h 8m stop
17:54 — 19:56
G42144
Allegiant Air
Miami — Knoxville
|
23h 12m including layover |
Find flight
from$128 |
|
|
19:00 — 16:47
+1 day
|
18:30 — 21:34
SY658
Sun Country Airlines
Denver — Minneapolis
11h 11m stop
08:30 — 11:53
SY1693
Sun Country Airlines
Minneapolis — Washington D.C.
2h 42m stop
15:13 — 16:47
G41398
Allegiant Air
Washington D.C. — Knoxville
|
19h 47m including layover |
Find flight
from$134 |
|
|
19:00 — 22:15
+1 day
|
19:00 — 22:01
SY658
Sun Country Airlines
Denver — Minneapolis
9h 47m stop
07:48 — 11:38
SY325
Sun Country Airlines
Minneapolis — Jacksonville
9h 17m stop
20:55 — 22:15
G41440
Allegiant Air
Jacksonville — Knoxville
|
25h 15m including layover |
Find flight
from$138 |
|
*Departure and arrival times - local. Updated on June 25, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from Denver to Knoxville depends on and how to choose the most interesting flight option for you.
Distance between Denver and Knoxville is 1866 miles. Time difference between the cities is 2h. Airplanes depart 05:02 to 23:59 from 2 Denver airports and arrive 05:02 to 23:59 to 1 Knoxville airport. Average flight time is 2h 47m.
- The fastest flight 2h 43m
- Average flight time 2h 47m
- The earliest flight 05:02
- The latest flight 23:59
- Distance 1160 ml
The cheapest months to travel to Knoxville are august (from 61 $), may (from 65 $), july (from 74 $).
The most expensive months are january (from 427 $), november (from 325 $), december (from 320 $).
What is the lowest airfare Denver to Knoxville?
The cheapest plane ticket found by our users is $45. This airfare is for economy class on one-way G41422 flight by Allegiant Air for August 7, 2025 which leaves Denver International in Denver at 17:42 am and arrives at Knoxville Mc Ghee Tyson at 22:27.
Economy class
$45
Business class
?
First class
?
Popular Airlines on the Route
The flight Denver — Knoxville is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 99 . And the most expensive tickets are offered by United Airlines airline - from $ 519.
Direct flights
There are 8 nonstop flights on the route. The fastest direct flight is G41438 by Allegiant Air takes 2h 43m and the cheapest is G41422 by Allegiant Air for $45.
- F9 - Frontier Airlinesfrom $99Find
- UA - United Airlinesfrom $138Find
- G4 - Allegiant Airfrom $45Find
See more direct flights
Connecting Flights
There are 241 flights with layovers on the route. The fastest connecting flight is UA2865 by United Airlines takes 5h 13m and the cheapest is G41422 by Allegiant Air for $87.
- SY - Sun Country Airlinesfrom $87Find
- LF - flynordicfrom $156Find
- KG - Aerogaviotafrom $171Find
- UA - United Airlinesfrom $196Find
- G4 - Allegiant Airfrom $120Find
See more connecting flights
Airports
You can fly from Denver to Knoxville from 2 airports (Denver International, Arapahoe Co).
Denver airports
- Denver International-DENfrom $45Find
- Arapahoe Co-APAFind
Knoxville airports
- Mc Ghee Tyson-TYSFind
Airplanes
There are flights to Knoxville from Denver by 6 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Denver
You may also consider searching for discounted plane tickets to some other popular places from Denver within United States.
- from $70Find
- from $59Find
- from $68Find
- from $75Find
- from $74Find
- from $66Find
- from $68Find
- from $57Find
- from $17Find
- from $67Find
Top International Destinations from Denver
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $66Find
- from $63Find
- from $75Find
- from $60Find
- from $60Find
- from $75Find
- from $66Find
- from $68Find
- from $69Find
- from $72Find
How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.