Cheap Flights from Buffalo, NY to San Diego, CA from $108

Return flight: San Diego – Buffalo

On Cheapflightsplus.com you will find 198 connecting flights from Buffalo to San Diego. You can compare airfare deals from 4 airlines and multiple travel sites from $108, book and save on cheap plane tickets and last minute offers. Also check out BUF-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Buffalo to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Buffalo and San Diego is 3528 miles. Time difference between the cities is 3h. Airplanes depart 05:10 to 19:55 from 1 Buffalo airport and arrive 05:10 to 19:55 to 11 San Diego airports. Average flight time is 12h 37m.

  • The fastest flight 7h 8m
  • Average flight time 12h 37m
  • The earliest flight 05:10
  • The latest flight 19:55
  • Distance 2193 ml

The cheapest months to travel to San Diego are may (from 108 $), july (from 137 $), june (from 195 $).

The most expensive months are february (from 330 $), january (from 326 $), august (from 219 $).

What is the lowest airfare Buffalo to San Diego?

The cheapest plane ticket found by our users is $108. This airfare is for economy class on one-way F92751 flight by Frontier Airlines for May 30, 2025 which leaves Niagara in Buffalo at 17:24 am and arrives at San Diego San Diego at 23:59.

Economy class
$108
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Business class
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First class
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Flight Schedule Buffalo (New York) to San Diego (California)

05:17 — 12:32
10h 15m flight time
Find flight
from$231
05:17 — 06:40 Buffalo — Washington D.C.
AS4141 Alaska Airlines
3h 19m stop
09:59 — 12:32 Washington D.C. — San Diego
AS15 Alaska Airlines
05:38 — 11:20
8h 42m flight time
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from$231
05:31 — 06:49 Buffalo — Washington D.C.
AS6860 Alaska Airlines
1h 59m stop
09:59 — 12:32 Washington D.C. — San Diego
AS15 Alaska Airlines
06:00 — 13:10
10h 10m flight time
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from$231
06:00 — 07:23 Buffalo — Newark
UA4181 United Airlines
3h stop
10:23 — 13:10 Newark — San Diego
UA2498 United Airlines
06:15 — 11:16
8h 1m flight time
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from$231
06:15 — 07:31 Buffalo — Washington D.C.
UA4298 United Airlines
1h 25m stop
08:56 — 11:16 Washington D.C. — San Diego
UA1930 United Airlines
06:15 — 11:16
8h 1m flight time
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from$231
06:15 — 07:29 Buffalo — Washington D.C.
UA4451 United Airlines
1h 27m stop
08:56 — 11:16 Washington D.C. — San Diego
UA1930 United Airlines
06:30 — 12:50
9h 20m flight time
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from$231
06:00 — 07:23 Buffalo — Newark
UA4181 United Airlines
2h 1m stop
07:00 — 09:41 Newark — San Diego
UA1826 United Airlines
07:00 — 11:23
7h 23m flight time
Find flight
from$231
07:00 — 08:03 Buffalo — Chicago
UA329 United Airlines
59m stop
08:50 — 11:28 Chicago — San Diego
UA660 United Airlines
08:33 — 12:57
7h 24m flight time
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from$231
08:33 — 10:09 Buffalo — Denver
UA1727 United Airlines
1h 24m stop
11:33 — 12:57 Denver — San Diego
UA1940 United Airlines
08:33 — 15:01
9h 28m flight time
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from$231
08:20 — 10:05 Buffalo — Denver
UA1727 United Airlines
3h 31m stop
13:33 — 14:57 Denver — San Diego
UA1302 United Airlines
11:47 — 16:25
7h 38m flight time
Find flight
from$187
11:41 — 13:00 Buffalo — Minneapolis
SY1058 Sun Country Airlines
1h 42m stop
15:12 — 17:03 Minneapolis — San Diego
SY407 Sun Country Airlines
12:16 — 11:01+1day
25h 45m flight time
Find flight
from$219
12:16 — 13:29 Buffalo — Minneapolis
SY1058 Sun Country Airlines
19h 49m stop
09:18 — 11:01 Minneapolis — San Diego
SY1639 Sun Country Airlines
14:10 — 19:39
8h 29m flight time
Find flight
from$113
17:24 — 19:13 Buffalo — Denver
F92751 Frontier Airlines
2h 8m stop
15:48 — 17:20 Denver — San Diego
F94989 Frontier Airlines
17:24 — 23:59
9h 35m flight time
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from$108
17:24 — 19:13 Buffalo — Denver
F92751 Frontier Airlines
3h 16m stop
22:29 — 23:59 Denver — San Diego
F92711 Frontier Airlines
17:24 — 09:55+1day
19h 31m flight time
Find flight
from$119
17:24 — 19:13 Buffalo — Denver
F92751 Frontier Airlines
13h 9m stop
08:22 — 09:55 Denver — San Diego
F92817 Frontier Airlines
17:57 — 22:14
7h 17m flight time
Find flight
from$226
17:51 — 18:47 Buffalo — Chicago
UA630 United Airlines
57m stop
19:50 — 22:14 Chicago — San Diego
UA630 United Airlines
Full flight schedule will help you in detecting at what time planes fly from Buffalo to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 23, 2025.

Popular Airlines on the Route

The flight Buffalo — San Diego is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 23 departures per week at the price of from $ 231 . And the most expensive tickets are offered by United Airlines airline - from $ 7639.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 198 flights with layovers on the route. The fastest connecting flight is UA514 by United Airlines takes 7h 8m and the cheapest is F92751 by Frontier Airlines for $108.

  • AS - Alaska Airlines
    from $231
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  • F9 - Frontier Airlines
    from $108
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  • SY - Sun Country Airlines
    from $185
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  • UA - United Airlines
    from $226
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See more connecting flights

Airports

You can fly from Buffalo to San Diego from 1 airports (Niagara).

Buffalo airports

  • Niagara-BUF
    from $108
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San Diego airports

  • San Diego-SAN
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  • San Diego Regional-USA
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  • Gillespie Field-SEE
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  • Golden Triangle Reg.-GTR
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  • El Cajon-CJN
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  • Lowndes County-UBS
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  • Miramar NAS-NKX
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  • Montgomery Field-MYF
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  • North Island NAS-NZY
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  • Brown Field Municipal-SDM
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  • AFB-CBM
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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