Cheap Flights from Buffalo, NY to San Diego, CA from $144

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On Cheapflightsplus.com you will find 100 connecting flights from Buffalo to San Diego. You can compare airfare deals from 4 airlines and multiple travel sites from $144, book and save on cheap plane tickets and last minute offers. Also check out BUF-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Buffalo to San Diego Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $144 (one-way), $247 (round-trip).

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Best Flights from Buffalo to San Diego Today

Take a look at the list of non stop flights and flights with layovers from Buffalo to San Diego with the lowest price of $144. Take a look at the list of flights with layovers from Buffalo to San Diego from $144. There’re no direct flights. The fastest connecting flight – 7h 8m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $144 Find flight	14:10 Buffalo Niagara	19:39 San Diego San Diego	8h 29m layover 2h 8m - Denver	Frontier Airlines	F92751 F94989
from $230 Find flight	12:16 Buffalo Niagara	11:01+1 день San Diego San Diego	25h 45m layover 19h 49m - Minneapolis	Sun Country Airlines	SY1058 SY1639
from $243 Find flight	17:54 Buffalo Niagara	22:02 San Diego San Diego	7h 8m layover 0h 45m - Chicago	United Airlines	UA514 UA734
from $243 Find flight	13:57 Buffalo Niagara	18:20 San Diego San Diego	7h 23m layover 1h 5m - Chicago	United Airlines	UA4381 UA2417
from $243 Find flight	08:33 Buffalo Niagara	12:57 San Diego San Diego	7h 24m layover 1h 24m - Denver	United Airlines	UA1727 UA1940
from $243 Find flight	10:55 Buffalo Niagara	15:50 San Diego San Diego	7h 55m layover 1h 39m - Chicago	United Airlines	UA1114 UA2683
from $243 Find flight	14:50 Buffalo Niagara	20:19 San Diego San Diego	8h 29m layover 1h 38m - Washington D.C.	United Airlines	UA4291 UA2054
from $243 Find flight	05:38 Buffalo Niagara	11:20 San Diego San Diego	8h 42m layover 1h 59m - Washington D.C.	Alaska Airlines	AS6860 AS15
from $243 Find flight	06:30 Buffalo Niagara	12:50 San Diego San Diego	9h 20m layover 2h 1m - Newark	United Airlines	UA4181 UA1826
from $243 Find flight	08:33 Buffalo Niagara	15:01 San Diego San Diego	9h 28m layover 3h 31m - Denver	United Airlines	UA1727 UA1302
from $250 Find flight	10:30 Buffalo Niagara	14:54 San Diego San Diego	7h 24m layover 0h 53m - Washington D.C.	United Airlines	UA4242 UA2736
from $250 Find flight	17:54 Buffalo Niagara	22:44 San Diego San Diego	7h 50m layover 1h 30m - Chicago	United Airlines	UA630 UA1842
from $194 Find flight	11:29 Buffalo Niagara	13:17+1 день San Diego San Diego	28h 48m layover 19h 18m - Minneapolis 2h 39m - Las Vegas	Sun Country Airlines	SY1058 SY103 NK2295
from $249 Find flight	10:30 Buffalo Niagara	18:23 San Diego San Diego	10h 53m layover 0h 49m - Washington D.C. 1h 22m - San Francisco	United Airlines	UA4282 UA1434 UA1434
from $249 Find flight	07:05 Buffalo Niagara	15:03 San Diego San Diego	10h 58m layover 0h 47m - Chicago 0h 45m - Washington D.C.	United Airlines	UA329 UA2029 UA2029
from $249 Find flight	08:33 Buffalo Niagara	20:48 San Diego San Diego	15h 15m layover 3h 21m - Denver 3h 58m - San Francisco	United Airlines	UA1727 UA1812 UA1812

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on July 04, 2025

Flight Schedule Buffalo (New York) to San Diego (California)

Full flight schedule will help you in detecting at what time planes fly from Buffalo to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
05:38 — 11:20	05:31 — 06:49 AS6860 Alaska Airlines Buffalo — Washington D.C. 1h 59m stop 09:59 — 12:32 AS15 Alaska Airlines Washington D.C. — San Diego	8h 42m including layover	Find flight from$243
06:00 — 10:55	06:00 — 07:14 UA4169 United Airlines Buffalo — Washington D.C. 1h 21m stop 08:35 — 10:55 UA1930 United Airlines Washington D.C. — San Diego	7h 55m including layover	Find flight from$250
06:30 — 12:50	06:00 — 07:23 UA4181 United Airlines Buffalo — Newark 2h 1m stop 07:00 — 09:41 UA1826 United Airlines Newark — San Diego	9h 20m including layover	Find flight from$243
07:05 — 18:20	07:00 — 07:56 UA329 United Airlines Buffalo — Chicago 7h 57m stop 16:05 — 18:27 UA2417 United Airlines Chicago — San Diego	14h 15m including layover	Find flight from$332
07:05 — 22:02	07:05 — 08:03 UA329 United Airlines Buffalo — Chicago 11h 32m stop 19:35 — 22:02 UA734 United Airlines Chicago — San Diego	17h 57m including layover	Find flight from$332
08:33 — 12:57	08:33 — 10:09 UA1727 United Airlines Buffalo — Denver 1h 24m stop 11:33 — 12:57 UA1940 United Airlines Denver — San Diego	7h 24m including layover	Find flight from$243
08:33 — 15:01	08:20 — 10:05 UA1727 United Airlines Buffalo — Denver 3h 31m stop 13:33 — 14:57 UA1302 United Airlines Denver — San Diego	9h 28m including layover	Find flight from$243
10:30 — 15:03	10:30 — 11:46 UA4282 United Airlines Buffalo — Washington D.C. 54m stop 12:40 — 15:03 UA2029 United Airlines Washington D.C. — San Diego	7h 33m including layover	Find flight from$243
10:55 — 15:50	10:55 — 11:51 UA1114 United Airlines Buffalo — Chicago 1h 39m stop 13:30 — 15:50 UA2683 United Airlines Chicago — San Diego	7h 55m including layover	Find flight from$243
11:22 — 19:07	10:51 — 12:10 UA4477 United Airlines Buffalo — Newark 3h 44m stop 16:36 — 19:18 UA1726 United Airlines Newark — San Diego	10h 45m including layover	Find flight from$283
11:47 — 16:25	11:41 — 13:00 SY1058 Sun Country Airlines Buffalo — Minneapolis 1h 42m stop 15:12 — 17:03 SY407 Sun Country Airlines Minneapolis — San Diego	7h 38m including layover	Find flight from$270
12:16 — 11:01 +1 day	12:16 — 13:29 SY1058 Sun Country Airlines Buffalo — Minneapolis 19h 49m stop 09:18 — 11:01 SY1639 Sun Country Airlines Minneapolis — San Diego	25h 45m including layover	Find flight from$230
13:57 — 18:20	13:57 — 14:55 UA4381 United Airlines Buffalo — Chicago 1h 5m stop 16:13 — 18:35 UA2417 United Airlines Chicago — San Diego	7h 23m including layover	Find flight from$243
13:57 — 22:02	13:57 — 14:55 UA4381 United Airlines Buffalo — Chicago 4h 40m stop 19:35 — 22:02 UA734 United Airlines Chicago — San Diego	11h 5m including layover	Find flight from$332
14:10 — 19:39	17:24 — 19:13 F92751 Frontier Airlines Buffalo — Denver 2h 8m stop 15:48 — 17:20 F94989 Frontier Airlines Denver — San Diego	8h 29m including layover	Find flight from$144
14:50 — 20:19	14:45 — 16:06 UA4291 United Airlines Buffalo — Washington D.C. 1h 38m stop 18:00 — 20:26 UA2054 United Airlines Washington D.C. — San Diego	8h 29m including layover	Find flight from$243
17:54 — 22:02	17:54 — 18:50 UA514 United Airlines Buffalo — Chicago 45m stop 19:35 — 22:02 UA734 United Airlines Chicago — San Diego	7h 8m including layover	Find flight from$243
17:54 — 22:44	17:54 — 18:50 UA630 United Airlines Buffalo — Chicago 1h 30m stop 20:20 — 22:44 UA1842 United Airlines Chicago — San Diego	7h 50m including layover	Find flight from$250

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on July 4, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Buffalo to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Buffalo and San Diego is 3528 miles. Time difference between the cities is 3h. Airplanes depart 05:38 to 17:54 from 1 Buffalo airport and arrive 05:38 to 17:54 to 11 San Diego airports. Average flight time is 11h 32m.

The fastest flight 7h 8m
Average flight time 11h 32m
The earliest flight 05:38
The latest flight 17:54
Distance 2193 ml

The cheapest months to travel to San Diego are may (from 119 $), july (from 144 $), june (from 207 $).

The most expensive months are august (from 230 $), june (from 207 $), july (from 144 $).

What is the lowest airfare Buffalo to San Diego?

The cheapest plane ticket found by our users is $144. This airfare is for economy class on one-way F92751 flight by Frontier Airlines for July 4, 2025 which leaves Niagara in Buffalo at 14:10 am and arrives at San Diego San Diego at 19:39.

Economy class

$144

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Business class

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First class

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Popular Airlines on the Route

The flight Buffalo — San Diego is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 1 departures per week at the price of from $ 243 . And the most expensive tickets are offered by United Airlines airline - from $ 8036.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 100 flights with layovers on the route. The fastest connecting flight is UA514 by United Airlines takes 7h 8m and the cheapest is F92751 by Frontier Airlines for $144.

AS - Alaska Airlines

from $243

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F9 - Frontier Airlines

from $144

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SY - Sun Country Airlines

from $194

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UA - United Airlines

from $243

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See more connecting flights

Airports

You can fly from Buffalo to San Diego from 1 airports (Niagara).

Buffalo airports

Niagara-BUF

from $144
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San Diego airports

San Diego-SAN

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San Diego Regional-USA

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Gillespie Field-SEE

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Golden Triangle Reg.-GTR

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El Cajon-CJN

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Lowndes County-UBS

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Miramar NAS-NKX

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Montgomery Field-MYF

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North Island NAS-NZY

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Brown Field Municipal-SDM

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AFB-CBM

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Airplanes

There are flights to San Diego from Buffalo by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Buffalo

You may also consider searching for discounted plane tickets to some other popular places from Buffalo within United States.

Buffalo — New York

from $58

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Buffalo — Orlando

from $61

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Buffalo — Las Vegas

from $62

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Buffalo — Tampa

from $70

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Buffalo — Miami

from $68

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Buffalo — Atlanta

from $68

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Buffalo — Boston

from $64

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Buffalo — Chicago

from $74

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Buffalo — Houston

from $68

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Buffalo — Charlotte

from $79

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Top International Destinations from Buffalo

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Buffalo — Toronto

from $54

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Buffalo — Cancun

from $60

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Buffalo — London

from $61

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Buffalo — Punta Cana

from $74

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Buffalo — Paris

from $59

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Buffalo — San Juan

from $60

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Buffalo — San Jose

from $72

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How to book a plane ticket yourself?

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That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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