Brussels Airlines San Francisco to Madrid Flights

Cheapflightsplus.com will find cheap Brussels Airlines flights from San Francisco to Madrid. Compare airline ticket prices and book air tickets starting from $440 from trusted online travel agencies, web sites and directly from airlines. Check flights schedule of Brussels Airlines, arrivals and departure details below.

Find Cheap Airfare San Francisco (CA) — Madrid by Brussels Airlines

To find cheap tickets choose a day of your departure with attractive price on the graph below and click «Find flights». For round trip flights please click «Check prices for return flight». The cheapest airfare is in january: one-way - $440, two-way – $755.
Direct flights
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Below is a detailed 2025 flight schedule for today, tomorrow and all other days. It may vary depending on season and a day of the week of your desired trip. We recommend booking your itinerary at least 2 weeks prior your travel to get the best price and availability by the airline.
Departure Arrival Flight Details Flight Time Price
12:50 pm — 1:25 pm
+1 day
12:50 pm — 7:25 am SN9105 Brussels Airlines
San Francisco — London
2h 35m stop
10:00 am — 1:25 pm BA468 British Airways
London — Madrid
15h 35m
including layover
Find flight
from$4850
12:50 pm — 7:50 pm
+1 day
12:50 pm — 7:25 am SN9105 Brussels Airlines
San Francisco — London
8h 55m stop
4:20 pm — 7:50 pm BA464 British Airways
London — Madrid
22h
including layover
Find flight
from$4850
12:50 pm — 6:20 pm
+1 day
12:50 pm — 7:25 am SN9105 Brussels Airlines
San Francisco — London
7h 25m stop
2:50 pm — 6:20 pm BA462 British Airways
London — Madrid
20h 30m
including layover
Find flight
from$4850
12:50 pm — 4:45 pm
+1 day
12:50 pm — 7:25 am SN9105 Brussels Airlines
San Francisco — London
5h 55m stop
1:20 pm — 4:45 pm BA460 British Airways
London — Madrid
18h 55m
including layover
Find flight
from$4850
2:40 pm — 11:25 pm
+1 day
2:40 pm — 10:30 am SN7249 Brussels Airlines
San Francisco — Frankfurt
2h 30m stop
1:00 pm — 2:00 pm SN7004 Brussels Airlines
Frankfurt — Brussels
6h 55m stop
8:55 pm — 11:25 pm SN3731 Brussels Airlines
Brussels — Madrid
23h 45m
including layover
Find flight
from$489
2:40 pm — 11:25 pm
+1 day
2:40 pm — 10:30 am SN7249 Brussels Airlines
San Francisco — Frankfurt
1h stop
11:30 am — 12:30 pm SN7018 Brussels Airlines
Frankfurt — Brussels
8h 25m stop
8:55 pm — 11:25 pm SN3731 Brussels Airlines
Brussels — Madrid
23h 45m
including layover
Find flight
from$489
2:40 pm — 7:35 pm
+1 day
2:40 pm — 10:30 am SN7249 Brussels Airlines
San Francisco — Frankfurt
1h 50m stop
12:20 pm — 1:55 pm SN7143 Brussels Airlines
Frankfurt — Budapest
2h 5m stop
4:00 pm — 7:35 pm W62371 Wizz Air
Budapest — Madrid
19h 55m
including layover
Find flight
from$514
2:40 pm — 4:45 pm
+1 day
2:40 pm — 10:30 am SN7249 Brussels Airlines
San Francisco — Frankfurt
1h stop
11:30 am — 12:30 pm SN7018 Brussels Airlines
Frankfurt — Brussels
1h 50m stop
2:20 pm — 4:45 pm SN3727 Brussels Airlines
Brussels — Madrid
17h 5m
including layover
Find flight
from$516
5:25 pm — 6:20 pm
+1 day
5:25 pm — 12:00 pm SN9103 Brussels Airlines
San Francisco — London
2h 50m stop
3:00 pm — 6:30 pm BA462 British Airways
London — Madrid
15h 55m
including layover
Find flight
from$4848
5:25 pm — 7:50 pm
+1 day
5:25 pm — 12:00 pm SN9103 Brussels Airlines
San Francisco — London
4h 20m stop
4:20 pm — 7:50 pm BA464 British Airways
London — Madrid
17h 25m
including layover
Find flight
from$4848
8:25 am — 11:45 am
+1 day
8:25 am — 4:28 pm SN8818 Brussels Airlines
San Francisco — Washington D.C.
1h 22m stop
5:50 pm — 7:15 am SN8802 Brussels Airlines
Washington D.C. — Brussels
2h 5m stop
9:20 am — 11:45 am SN3721 Brussels Airlines
Brussels — Madrid
18h 20m
including layover
Find flight
from$551
8:30 am — 11:45 am
+1 day
8:30 am — 4:58 pm SN9590 Brussels Airlines
San Francisco — Montreal
1h 42m stop
6:40 pm — 7:55 am SN9552 Brussels Airlines
Montreal — Brussels
1h 25m stop
9:20 am — 11:45 am SN3721 Brussels Airlines
Brussels — Madrid
18h 15m
including layover
Find flight
from$440
8:30 am — 11:25 pm
+1 day
8:30 am — 4:58 pm SN9590 Brussels Airlines
San Francisco — Montreal
1h 42m stop
6:40 pm — 7:55 am SN9552 Brussels Airlines
Montreal — Brussels
13h stop
8:55 pm — 11:25 pm SN3731 Brussels Airlines
Brussels — Madrid
29h 55m
including layover
Find flight
from$453
8:35 pm — 11:25 pm
+1 day
8:35 pm — 4:35 pm SN7253 Brussels Airlines
San Francisco — Munich
1h 25m stop
6:00 pm — 7:25 pm SN7060 Brussels Airlines
Munich — Brussels
1h 30m stop
8:55 pm — 11:25 pm SN3731 Brussels Airlines
Brussels — Madrid
17h 50m
including layover
Find flight
from$515
9:00 am — 9:15 am
+1 day
8:40 am — 5:02 pm SN8942 Brussels Airlines
San Francisco — Newark
2h 15m stop
7:50 pm — 9:15 am SN9027 Brussels Airlines
Newark — Madrid
15h 15m
including layover
Find flight
from$525
9:00 am — 11:45 am
+1 day
8:40 am — 5:02 pm SN8942 Brussels Airlines
San Francisco — Newark
1h 40m stop
7:00 pm — 8:05 am SN8808 Brussels Airlines
Newark — Brussels
1h 15m stop
9:20 am — 11:45 am SN3721 Brussels Airlines
Brussels — Madrid
17h 45m
including layover
Find flight
from$551
9:00 am — 9:15 am
+1 day
7:15 am — 3:30 pm SN8912 Brussels Airlines
San Francisco — Newark
2h 30m stop
7:50 pm — 9:15 am SN9027 Brussels Airlines
Newark — Madrid
15h 15m
including layover
Find flight
from$575
9:00 am — 11:45 am
+1 day
9:00 am — 5:20 pm SN8912 Brussels Airlines
San Francisco — Newark
1h 40m stop
7:00 pm — 8:05 am SN8808 Brussels Airlines
Newark — Brussels
1h 15m stop
9:20 am — 11:45 am SN3721 Brussels Airlines
Brussels — Madrid
17h 45m
including layover
Find flight
from$727
*Departure and arrival times are local. Last updated on 12/22/2024

Flight Information

There are 19 flights by Brussels Airlines from San Francisco to Madrid every week with departures from San Francisco, Embarkadero, China Basin Heliport. All flights arrive at Barajas and Torrejon.

Departures start from 12:50 pm to 9:00 am. Nonstop flight is 15h 15m. The time difference between San Francisco and Madrid is 9h.

  • The fastest flight 15h 15m
  • Average flight time 18h 3m
  • The earliest flight 12:50 pm
  • The latest flight 9:00 am
  • Distance 5798 ml

The cheapest months for traveling to Madrid are january (from 440 $), november (from 450 $), december (from 482 $).

The most expensive and popular months are february (from 515 $), december (from 482 $), november (from 450 $).

The cheapest flight by Brussels Airlines that our users were able to find is $440. This airfare is economy class on one-way SN9590 flight for January 22, 2025 leaving San Francisco in San Francisco at 8:30 am, it includes all taxes and additional fees.

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Other Popular Airlines on the Route

Besides Brussels Airlines there are other 17 airline carriers between San Francisco and Madrid. Please review schedules and prices from the most popular airlines to find the best airfare deals from San Francisco to Madrid.

Nonstop flights

There’re no direct flights on this route. Try flights with stops.

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Connecting Flights

List of flights with layovers (1 and more stops):

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How to book an air ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected airfare.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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