American Airlines Philadelphia to Des Moines Flights

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Cheapflightsplus.com will find cheap American Airlines flights from Philadelphia to Des Moines. Compare airline ticket prices and book air tickets starting from $149 from trusted online travel agencies, web sites and directly from airlines. Check flights schedule of American Airlines, arrivals and departure details below.

Find Cheap Airfare Philadelphia (PA) — Des Moines (IA) by American Airlines

To find cheap tickets choose a day of your departure with attractive price on the graph below and click «Find flights». For round trip flights please click «Check prices for return flight». The cheapest airfare is in january: one-way - $149, two-way – $256.

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Cheap Flights from Philadelphia to Des Moines by American Airlines

Look at the list of plane tickets for the most popular direct and connecting flights by American Airlines, their prices start from $149. The fastest nonstop flight takes 2h 52m. The fastest connecting flight — 4h 30m.

Price	Departure	Arrival	Flight Time	Airline	Flight
from $149 Find flight	10:50 am Philadelphia Philadelphia Int.	12:42 pm Des Moines Des Moines International Airport	2h 52m	American Airlines	AA4383
from $184 Find flight	6:49 pm Philadelphia Philadelphia Int.	8:50 pm Des Moines Des Moines International Airport	3h 1m	American Airlines	AA4596
from $154 Find flight	7:00 am Philadelphia Philadelphia Int.	11:29 am Des Moines Des Moines International Airport	5h 29m layover 1h 4m - Charlotte	American Airlines	AA563 AA5421
from $155 Find flight	6:05 am Philadelphia Philadelphia Int.	11:53 am Des Moines Des Moines International Airport	6h 48m layover 3h 12m - Chicago	American Airlines	AA892 AA3407
from $165 Find flight	8:45 am Philadelphia Philadelphia Int.	1:44 pm Des Moines Des Moines International Airport	5h 59m layover 1h 59m - Chicago	American Airlines	AA698 AA4144
from $190 Find flight	7:45 am Philadelphia Philadelphia Int.	11:53 am Des Moines Des Moines International Airport	5h 8m layover 1h 24m - Chicago	American Airlines	AA2098 AA3407
from $218 Find flight	8:40 am Philadelphia Philadelphia Int.	2:40 pm Des Moines Des Moines International Airport	7h 0m layover 2h 33m - Charlotte	American Airlines	AA773 AA5192
from $218 Find flight	5:10 pm Philadelphia Philadelphia Int.	11:43 pm Des Moines Des Moines International Airport	7h 33m layover 3h 16m - Charlotte	American Airlines	AA1648 AA5273
from $219 Find flight	11:01 am Philadelphia Philadelphia Int.	4:32 pm Des Moines Des Moines International Airport	6h 31m layover 2h 36m - Chicago	American Airlines	AA2095 AA2995
from $219 Find flight	12:46 pm Philadelphia Philadelphia Int.	4:32 pm Des Moines Des Moines International Airport	4h 46m layover 1h 1m - Chicago	American Airlines	AA2011 AA2995
from $253 Find flight	3:43 pm Philadelphia Philadelphia Int.	10:05 pm Des Moines Des Moines International Airport	7h 22m layover 3h 19m - Chicago	American Airlines	AA2181 AA3495
from $255 Find flight	8:10 am Philadelphia Philadelphia Int.	1:44 pm Des Moines Des Moines International Airport	6h 34m layover 1h 3m - Dayton 1h 11m - Chicago	American Airlines	AA5581 AA3364 AA4144
from $255 Find flight	9:31 am Philadelphia Philadelphia Int.	4:32 pm Des Moines Des Moines International Airport	8h 1m layover 2h 2m - Washington D.C. 1h 12m - Chicago	American Airlines	AA4606 AA985 AA2995
from $255 Find flight	10:29 am Philadelphia Philadelphia Int.	4:32 pm Des Moines Des Moines International Airport	7h 3m layover 1h 17m - Detroit 0h 56m - Chicago	American Airlines	AA4865 AA3084 AA2995
from $255 Find flight	3:35 pm Philadelphia Philadelphia Int.	10:05 pm Des Moines Des Moines International Airport	7h 30m layover 1h 28m - Detroit 1h 10m - Chicago	American Airlines	AA1927 AA3101 AA3495
from $255 Find flight	3:49 pm Philadelphia Philadelphia Int.	10:05 pm Des Moines Des Moines International Airport	7h 16m layover 1h 40m - Dayton 1h 2m - Chicago	American Airlines	AA5107 AA4193 AA3495

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*Departure and arrival times are local. Prices are for one-way flights. Information refreshed on 01/15/2025

American Airlines Flight Schedule Philadelphia to Des Moines

Below is a detailed 2025 flight schedule for today, tomorrow and all other days. It may vary depending on season and a day of the week of your desired trip. We recommend booking your itinerary at least 2 weeks prior your travel to get the best price and availability by the airline.

Departure	Flight Details	Flight Time	Price
10:50 am — 12:42 pm	10:50 am — 12:42 pm AA4383 American Airlines Philadelphia — Des Moines	2h 52m	Find flight from$149
6:49 pm — 8:50 pm	6:49 pm — 8:50 pm AA4596 American Airlines Philadelphia — Des Moines	3h 1m	Find flight from$184
11:01 am — 4:32 pm	11:01 am — 12:34 pm AA2095 American Airlines Philadelphia — Chicago 2h 36m stop 3:10 pm — 4:32 pm AA2995 American Airlines Chicago — Des Moines	6h 31m including layover	Find flight from$219
11:01 am — 10:05 pm	11:01 am — 12:34 pm AA2095 American Airlines Philadelphia — Chicago 8h 6m stop 8:40 pm — 10:05 pm AA3495 American Airlines Chicago — Des Moines	12h 4m including layover	Find flight from$256
12:46 pm — 4:32 pm	12:46 pm — 2:09 pm AA2011 American Airlines Philadelphia — Chicago 1h 1m stop 3:10 pm — 4:32 pm AA2995 American Airlines Chicago — Des Moines	4h 46m including layover	Find flight from$219
12:46 pm — 10:05 pm	12:46 pm — 2:09 pm AA2011 American Airlines Philadelphia — Chicago 6h 31m stop 8:40 pm — 10:05 pm AA3495 American Airlines Chicago — Des Moines	10h 19m including layover	Find flight from$256
3:43 pm — 10:05 pm	3:43 pm — 5:21 pm AA2181 American Airlines Philadelphia — Chicago 3h 19m stop 8:40 pm — 10:05 pm AA3495 American Airlines Chicago — Des Moines	7h 22m including layover	Find flight from$253
4:30 pm — 9:47 pm	4:30 pm — 5:33 pm AA1787 American Airlines Philadelphia — Washington D.C. 2h 32m stop 8:05 pm — 9:47 pm AA4518 American Airlines Washington D.C. — Des Moines	6h 17m including layover	Find flight from$346
5:00 am — 4:32 pm	5:00 am — 6:10 am AA2324 American Airlines Philadelphia — Chicago 9h stop 3:10 pm — 4:32 pm AA2995 American Airlines Chicago — Des Moines	12h 32m including layover	Find flight from$256
5:10 pm — 11:43 pm	5:10 pm — 6:59 pm AA1648 American Airlines Philadelphia — Charlotte 3h 16m stop 10:15 pm — 11:43 pm AA5273 American Airlines Charlotte — Des Moines	7h 33m including layover	Find flight from$218
6:05 am — 11:53 am	6:05 am — 7:23 am AA892 American Airlines Philadelphia — Chicago 3h 12m stop 10:35 am — 11:53 am AA3407 American Airlines Chicago — Des Moines	6h 48m including layover	Find flight from$155
7:00 am — 11:29 am	7:00 am — 8:46 am AA563 American Airlines Philadelphia — Charlotte 1h 4m stop 9:50 am — 11:29 am AA5421 American Airlines Charlotte — Des Moines	5h 29m including layover	Find flight from$154
7:45 am — 1:44 pm	7:45 am — 9:11 am AA2098 American Airlines Philadelphia — Chicago 3h 9m stop 12:20 pm — 1:44 pm AA4144 American Airlines Chicago — Des Moines	6h 59m including layover	Find flight from$155
8:40 am — 2:40 pm	8:40 am — 10:37 am AA773 American Airlines Philadelphia — Charlotte 2h 33m stop 1:10 pm — 2:40 pm AA5192 American Airlines Charlotte — Des Moines	7h including layover	Find flight from$218
8:45 am — 1:44 pm	8:45 am — 10:21 am AA698 American Airlines Philadelphia — Chicago 1h 59m stop 12:20 pm — 1:44 pm AA4144 American Airlines Chicago — Des Moines	5h 59m including layover	Find flight from$165
9:25 pm — 4:32 pm +1 day	9:25 pm — 10:49 pm AA1680 American Airlines Philadelphia — Chicago 16h 21m stop 3:10 pm — 4:32 pm AA2995 American Airlines Chicago — Des Moines	20h 7m including layover	Find flight from$256
10:29 am — 4:32 pm	10:29 am — 12:27 pm AA4865 American Airlines Philadelphia — Detroit 1h 17m stop 1:44 pm — 2:14 pm AA3084 American Airlines Detroit — Chicago 56m stop 3:10 pm — 4:32 pm AA2995 American Airlines Chicago — Des Moines	7h 3m including layover	Find flight from$255
1:10 pm — 6:54 pm	1:10 pm — 2:47 pm AA5398 American Airlines Philadelphia — Dayton 1h 5m stop 3:52 pm — 4:14 pm AA5430 American Airlines Dayton — Chicago 1h 21m stop 5:35 pm — 6:54 pm AA3455 American Airlines Chicago — Des Moines	6h 44m including layover	Find flight from$377
1:15 pm — 6:54 pm	1:15 pm — 2:50 pm AA4425 American Airlines Philadelphia — Columbus 31m stop 3:21 pm — 3:44 pm AA3399 American Airlines Columbus — Chicago 1h 51m stop 5:35 pm — 6:54 pm AA3455 American Airlines Chicago — Des Moines	6h 39m including layover	Find flight from$412
2:30 pm — 10:41 pm	2:30 pm — 3:50 pm AA1923 American Airlines Philadelphia — Lake Saint Louis 1h 27m stop 5:17 pm — 7:14 pm AA1616 American Airlines Lake Saint Louis — Dallas 1h 36m stop 8:50 pm — 10:41 pm AA1371 American Airlines Dallas — Des Moines	9h 11m including layover	Find flight from$543
3:35 pm — 10:05 pm	3:35 pm — 5:27 pm AA1927 American Airlines Philadelphia — Detroit 1h 28m stop 6:55 pm — 7:30 pm AA3101 American Airlines Detroit — Chicago 1h 10m stop 8:40 pm — 10:05 pm AA3495 American Airlines Chicago — Des Moines	7h 30m including layover	Find flight from$255
4:29 pm — 10:05 pm	4:29 pm — 5:45 pm AA1713 American Airlines Philadelphia — Pittsburgh 1h 17m stop 7:02 pm — 7:47 pm AA3402 American Airlines Pittsburgh — Chicago 53m stop 8:40 pm — 10:05 pm AA3495 American Airlines Chicago — Des Moines	6h 36m including layover	Find flight from$380
9:31 am — 4:32 pm	9:31 am — 10:38 am AA4606 American Airlines Philadelphia — Washington D.C. 2h 2m stop 12:40 pm — 1:58 pm AA985 American Airlines Washington D.C. — Chicago 1h 12m stop 3:10 pm — 4:32 pm AA2995 American Airlines Chicago — Des Moines	8h 1m including layover	Find flight from$255

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times are local. Last updated on 01/15/2025

Flight Information

There are 2 flights by American Airlines from Philadelphia to Des Moines every week with departures from Philadelphia Int., Mustin Alf, North Philadelphia, Philadelphia Sea Plane Base. All flights arrive at Des Moines International Airport.

Departures start from 10:20 am to 9:50 am. Nonstop flight is 2h 52m. The time difference between Philadelphia and Des Moines is 1h.

The fastest flight 2h 52m
Average flight time 2h 57m
The earliest flight 10:20 am
The latest flight 9:50 am
Distance 970 ml

The cheapest flight by American Airlines that our users were able to find is $149. This airfare is economy class on one-way AA4383 flight for October 21, 2018 leaving Philadelphia Int. in Philadelphia at 10:50 am, it includes all taxes and additional fees.

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American Airlines Airplanes on the Route

List of the most popular American Airlines airplanes flying from Philadelphia to Des Moines:

Embraer 175 (short wing)

from $149

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Airbus A321

from $154

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Boeing 737

from $256

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Airbus A319

from $264

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Airbus A320

from $264

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Canadair Regional Jet 700

from $300

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Canadair Regional Jet 900

from $308

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Embraer 190

from $346

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Boeing 737-800

from $386

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Other Popular Airlines on the Route

Besides American Airlines there are other 2 airline carriers between Philadelphia and Des Moines. Please review schedules and prices from the most popular airlines to find the best airfare deals from Philadelphia to Des Moines.

Nonstop flights

There are 2 direct flights every day from Philadelphia. Airlines and fares are below:

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Connecting Flights

List of flights with layovers (1 and more stops):

F9 - Frontier Airlines

from $54

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UA - United Airlines

from $222

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How to book an air ticket yourself?

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