American Airlines Philadelphia to Des Moines Flights

Cheapflightsplus.com will find cheap American Airlines flights from Philadelphia to Des Moines. Compare airline ticket prices and book air tickets starting from $127 from trusted online travel agencies, web sites and directly from airlines. Check flights schedule of American Airlines, arrivals and departure details below.

Find Cheap Airfare Philadelphia (PA) — Des Moines (IA) by American Airlines

To find cheap tickets choose a day of your departure with attractive price on the graph below and click «Find flights». For round trip flights please click «Check prices for return flight». The cheapest airfare is in may: one-way - $127, two-way – $218.
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Below is a detailed 2024 flight schedule for today, tomorrow and all other days. It may vary depending on season and a day of the week of your desired trip. We recommend booking your itinerary at least 2 weeks prior your travel to get the best price and availability by the airline.
Departure Arrival Flight Details Flight Time Price
10:50 am — 12:42 pm
10:50 am — 12:42 pm AA4383 American Airlines
Philadelphia — Des Moines
2h 52m
Find flight
from$166
6:49 pm — 8:50 pm
6:49 pm — 8:50 pm AA4596 American Airlines
Philadelphia — Des Moines
3h 1m
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from$205
11:01 am — 4:32 pm
11:01 am — 12:34 pm AA2095 American Airlines
Philadelphia — Chicago
2h 36m stop
3:10 pm — 4:32 pm AA2995 American Airlines
Chicago — Des Moines
6h 31m
including layover
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from$243
11:01 am — 10:05 pm
11:01 am — 12:34 pm AA2095 American Airlines
Philadelphia — Chicago
8h 6m stop
8:40 pm — 10:05 pm AA3495 American Airlines
Chicago — Des Moines
12h 4m
including layover
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from$285
12:46 pm — 4:32 pm
12:46 pm — 2:09 pm AA2011 American Airlines
Philadelphia — Chicago
1h 1m stop
3:10 pm — 4:32 pm AA2995 American Airlines
Chicago — Des Moines
4h 46m
including layover
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from$243
12:46 pm — 10:05 pm
12:46 pm — 2:09 pm AA2011 American Airlines
Philadelphia — Chicago
6h 31m stop
8:40 pm — 10:05 pm AA3495 American Airlines
Chicago — Des Moines
10h 19m
including layover
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from$285
3:43 pm — 10:05 pm
3:43 pm — 5:21 pm AA2181 American Airlines
Philadelphia — Chicago
3h 19m stop
8:40 pm — 10:05 pm AA3495 American Airlines
Chicago — Des Moines
7h 22m
including layover
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from$281
4:30 pm — 9:47 pm
4:30 pm — 5:33 pm AA1787 American Airlines
Philadelphia — Washington D.C.
2h 32m stop
8:05 pm — 9:47 pm AA4518 American Airlines
Washington D.C. — Des Moines
6h 17m
including layover
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from$384
5:09 am — 11:23 am
5:09 am — 6:50 am AA1809 American Airlines
Philadelphia — Charlotte
2h 50m stop
9:40 am — 11:23 am AA5421 American Airlines
Charlotte — Des Moines
7h 14m
including layover
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from$127
5:54 pm — 9:47 pm
5:54 pm — 7:10 pm AA4515 American Airlines
Philadelphia — Washington D.C.
56m stop
8:06 pm — 9:47 pm AA4518 American Airlines
Washington D.C. — Des Moines
4h 53m
including layover
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from$129
6:05 am — 11:53 am
6:05 am — 7:23 am AA892 American Airlines
Philadelphia — Chicago
3h 12m stop
10:35 am — 11:53 am AA3407 American Airlines
Chicago — Des Moines
6h 48m
including layover
Find flight
from$172
6:15 am — 11:26 am
6:15 am — 8:01 am AA563 American Airlines
Philadelphia — Charlotte
1h 40m stop
9:41 am — 11:26 am AA5421 American Airlines
Charlotte — Des Moines
6h 11m
including layover
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from$127
7:00 am — 11:29 am
7:00 am — 8:46 am AA563 American Airlines
Philadelphia — Charlotte
1h 4m stop
9:50 am — 11:29 am AA5421 American Airlines
Charlotte — Des Moines
5h 29m
including layover
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from$171
7:45 am — 1:44 pm
7:45 am — 9:11 am AA2098 American Airlines
Philadelphia — Chicago
3h 9m stop
12:20 pm — 1:44 pm AA4144 American Airlines
Chicago — Des Moines
6h 59m
including layover
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from$172
8:40 am — 2:40 pm
8:40 am — 10:37 am AA773 American Airlines
Philadelphia — Charlotte
2h 33m stop
1:10 pm — 2:40 pm AA5192 American Airlines
Charlotte — Des Moines
7h
including layover
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from$242
8:45 am — 1:44 pm
8:45 am — 10:21 am AA698 American Airlines
Philadelphia — Chicago
1h 59m stop
12:20 pm — 1:44 pm AA4144 American Airlines
Chicago — Des Moines
5h 59m
including layover
Find flight
from$183
9:25 pm — 4:32 pm
+1 day
9:25 pm — 10:49 pm AA1680 American Airlines
Philadelphia — Chicago
16h 21m stop
3:10 pm — 4:32 pm AA2995 American Airlines
Chicago — Des Moines
20h 7m
including layover
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from$285
10:29 am — 4:32 pm
10:29 am — 12:27 pm AA4865 American Airlines
Philadelphia — Detroit
1h 17m stop
1:44 pm — 2:14 pm AA3084 American Airlines
Detroit — Chicago
56m stop
3:10 pm — 4:32 pm AA2995 American Airlines
Chicago — Des Moines
7h 3m
including layover
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from$284
1:10 pm — 6:54 pm
1:10 pm — 2:47 pm AA5398 American Airlines
Philadelphia — Dayton
1h 5m stop
3:52 pm — 4:14 pm AA5430 American Airlines
Dayton — Chicago
1h 21m stop
5:35 pm — 6:54 pm AA3455 American Airlines
Chicago — Des Moines
6h 44m
including layover
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from$419
1:15 pm — 6:54 pm
1:15 pm — 2:50 pm AA4425 American Airlines
Philadelphia — Columbus
31m stop
3:21 pm — 3:44 pm AA3399 American Airlines
Columbus — Chicago
1h 51m stop
5:35 pm — 6:54 pm AA3455 American Airlines
Chicago — Des Moines
6h 39m
including layover
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from$458
2:30 pm — 10:41 pm
2:30 pm — 3:50 pm AA1923 American Airlines
Philadelphia — Lake Saint Louis
1h 27m stop
5:17 pm — 7:14 pm AA1616 American Airlines
Lake Saint Louis — Dallas
1h 36m stop
8:50 pm — 10:41 pm AA1371 American Airlines
Dallas — Des Moines
9h 11m
including layover
Find flight
from$603
3:35 pm — 10:05 pm
3:35 pm — 5:27 pm AA1927 American Airlines
Philadelphia — Detroit
1h 28m stop
6:55 pm — 7:30 pm AA3101 American Airlines
Detroit — Chicago
1h 10m stop
8:40 pm — 10:05 pm AA3495 American Airlines
Chicago — Des Moines
7h 30m
including layover
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from$284
4:29 pm — 10:05 pm
4:29 pm — 5:45 pm AA1713 American Airlines
Philadelphia — Pittsburgh
1h 17m stop
7:02 pm — 7:47 pm AA3402 American Airlines
Pittsburgh — Chicago
53m stop
8:40 pm — 10:05 pm AA3495 American Airlines
Chicago — Des Moines
6h 36m
including layover
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from$422
9:31 am — 4:32 pm
9:31 am — 10:38 am AA4606 American Airlines
Philadelphia — Washington D.C.
2h 2m stop
12:40 pm — 1:58 pm AA985 American Airlines
Washington D.C. — Chicago
1h 12m stop
3:10 pm — 4:32 pm AA2995 American Airlines
Chicago — Des Moines
8h 1m
including layover
Find flight
from$284
*Departure and arrival times are local. Last updated on 05/13/2024

Flight Information

There are 2 flights by American Airlines from Philadelphia to Des Moines every week with departures from Philadelphia Int., Mustin Alf, North Philadelphia, Philadelphia Sea Plane Base. All flights arrive at Des Moines International Airport.

Departures start from 10:20 am to 9:50 am. Nonstop flight is 2h 52m. The time difference between Philadelphia and Des Moines is 1h.

  • The fastest flight 2h 52m
  • Average flight time 2h 57m
  • The earliest flight 10:20 am
  • The latest flight 9:50 am
  • Distance 970 ml

The cheapest flight by American Airlines that our users were able to find is $127. This airfare is economy class on one-way AA563 flight for July 22, 2020 leaving Philadelphia Int. in Philadelphia at 6:15 am, it includes all taxes and additional fees.

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Other Popular Airlines on the Route

American Airlines is the only airline which provides flights on the route Philadelphia — Des Moines. To choose the best flight cost and time we advise to get acquainted with its schedule and prices.

Nonstop flights

There are 2 direct flights every day from Philadelphia. Airlines and fares are below:

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Connecting Flights

List of flights with layovers (1 and more stops):

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How to book an air ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected airfare.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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