American Airlines Orlando to Des Moines Flights

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Best Airfare Price Calendar Flights Schedule

Cheapflightsplus.com will find cheap American Airlines flights from Orlando to Des Moines. Compare airline ticket prices and book air tickets starting from $102 from trusted online travel agencies, web sites and directly from airlines. Check flights schedule of American Airlines, arrivals and departure details below.

Find Cheap Airfare Orlando (FL) — Des Moines (IA) by American Airlines

To find cheap tickets choose a day of your departure with attractive price on the graph below and click «Find flights». For round trip flights please click «Check prices for return flight». The cheapest airfare is in january: one-way - $102, two-way – $175.

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Cheap Flights from Orlando to Des Moines by American Airlines

Look at the list of plane tickets for the most connecting flights by American Airlines, their prices start from $102. There’re no direct flights. The fastest connecting flight – 5h 21m.

Price	Departure	Arrival	Flight Time	Airline	Flight
from $103 Find flight	6:00 am Orlando Orlando Int.	11:29 am Des Moines Des Moines International Airport	6h 29m layover 2h 7m - Charlotte	American Airlines	AA1896 AA5421
from $104 Find flight	8:27 am Orlando Orlando Int.	2:40 pm Des Moines Des Moines International Airport	7h 13m layover 2h 56m - Charlotte	American Airlines	AA461 AA5192
from $104 Find flight	10:19 am Orlando Orlando Int.	2:40 pm Des Moines Des Moines International Airport	5h 21m layover 1h 7m - Charlotte	American Airlines	AA2114 AA5192
from $104 Find flight	5:15 pm Orlando Orlando Int.	11:43 pm Des Moines Des Moines International Airport	7h 28m layover 3h 15m - Charlotte	American Airlines	AA677 AA5273
from $104 Find flight	7:17 pm Orlando Orlando Int.	11:43 pm Des Moines Des Moines International Airport	5h 26m layover 1h 15m - Charlotte	American Airlines	AA1939 AA5273
from $104 Find flight	7:40 am Orlando Orlando Int.	12:30 pm Des Moines Des Moines International Airport	5h 50m layover 1h 1m - Dallas	American Airlines	AA1024 AA1281
from $104 Find flight	11:50 am Orlando Orlando Int.	4:34 pm Des Moines Des Moines International Airport	5h 44m layover 1h 5m - Dallas	American Airlines	AA2489 AA2388
from $104 Find flight	2:32 pm Orlando Orlando Int.	8:50 pm Des Moines Des Moines International Airport	7h 18m layover 1h 50m - Philadelphia	American Airlines	AA588 AA4596
from $105 Find flight	5:56 am Orlando Orlando Int.	12:30 pm Des Moines Des Moines International Airport	7h 34m layover 2h 48m - Dallas	American Airlines	AA2673 AA1281
from $105 Find flight	6:00 am Orlando Orlando Int.	12:42 pm Des Moines Des Moines International Airport	7h 42m layover 2h 24m - Philadelphia	American Airlines	AA1832 AA4413
from $105 Find flight	7:26 am Orlando Orlando Int.	12:42 pm Des Moines Des Moines International Airport	6h 16m layover 0h 57m - Philadelphia	American Airlines	AA1881 AA4413
from $105 Find flight	9:07 am Orlando Orlando Int.	4:34 pm Des Moines Des Moines International Airport	8h 27m layover 3h 41m - Dallas	American Airlines	AA2075 AA2388
from $126 Find flight	8:48 am Orlando Orlando Int.	1:44 pm Des Moines Des Moines International Airport	5h 56m layover 1h 31m - Chicago	American Airlines	AA153 AA4144
from $146 Find flight	7:02 am Orlando Orlando Int.	1:44 pm Des Moines Des Moines International Airport	7h 42m layover 3h 11m - Chicago	American Airlines	AA2721 AA4144
from $102 Find flight	5:06 am Orlando Orlando Int.	11:08 am Des Moines Des Moines International Airport	7h 2m layover 0h 58m - Charlotte 1h 2m - Chicago	American Airlines	AA2090 AA462 AA3064
from $129 Find flight	11:55 am Orlando Orlando Int.	10:41 pm Des Moines Des Moines International Airport	11h 46m layover 2h 31m - Charlotte 2h 48m - Dallas	American Airlines	AA1849 AA1618 AA1371

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*Departure and arrival times are local. Prices are for one-way flights. Information refreshed on 01/20/2025

American Airlines Flight Schedule Orlando to Des Moines

Below is a detailed 2025 flight schedule for today, tomorrow and all other days. It may vary depending on season and a day of the week of your desired trip. We recommend booking your itinerary at least 2 weeks prior your travel to get the best price and availability by the airline.

Departure	Flight Details	Flight Time	Price
10:19 am — 2:40 pm	10:19 am — 12:03 pm AA2114 American Airlines Orlando — Charlotte 1h 7m stop 1:10 pm — 2:40 pm AA5192 American Airlines Charlotte — Des Moines	5h 21m including layover	Find flight from$104
11:50 am — 4:34 pm	11:50 am — 1:39 pm AA2489 American Airlines Orlando — Dallas 1h 5m stop 2:44 pm — 4:34 pm AA2388 American Airlines Dallas — Des Moines	5h 44m including layover	Find flight from$104
2:32 pm — 8:50 pm	2:32 pm — 4:59 pm AA588 American Airlines Orlando — Philadelphia 1h 50m stop 6:49 pm — 8:50 pm AA4596 American Airlines Philadelphia — Des Moines	7h 18m including layover	Find flight from$104
2:44 pm — 9:43 pm	2:44 pm — 4:59 pm AA2016 American Airlines Orlando — Washington D.C. 3h 6m stop 8:05 pm — 9:43 pm AA4518 American Airlines Washington D.C. — Des Moines	7h 59m including layover	Find flight from$146
3:50 pm — 11:22 pm	3:50 pm — 5:45 pm AA2538 American Airlines Orlando — Dallas 3h 54m stop 9:39 pm — 11:22 pm AA1371 American Airlines Dallas — Des Moines	8h 32m including layover	Find flight from$105
4:23 pm — 12:42 pm +1 day	4:23 pm — 6:54 pm AA1848 American Airlines Orlando — Philadelphia 15h 56m stop 10:50 am — 12:42 pm AA4413 American Airlines Philadelphia — Des Moines	21h 19m including layover	Find flight from$257
5:00 am — 11:29 am	5:00 am — 6:36 am AA2090 American Airlines Orlando — Charlotte 3h 14m stop 9:50 am — 11:29 am AA5421 American Airlines Charlotte — Des Moines	7h 29m including layover	Find flight from$104
6:00 am — 11:29 am	6:00 am — 7:43 am AA1896 American Airlines Orlando — Charlotte 2h 7m stop 9:50 am — 11:29 am AA5421 American Airlines Charlotte — Des Moines	6h 29m including layover	Find flight from$103
6:00 am — 12:42 pm	6:00 am — 8:26 am AA1832 American Airlines Orlando — Philadelphia 2h 24m stop 10:50 am — 12:42 pm AA4413 American Airlines Philadelphia — Des Moines	7h 42m including layover	Find flight from$105
7:02 am — 11:53 am	7:02 am — 9:09 am AA2721 American Airlines Orlando — Chicago 1h 26m stop 10:35 am — 11:53 am AA3407 American Airlines Chicago — Des Moines	5h 51m including layover	Find flight from$104
7:17 pm — 11:43 pm	7:17 pm — 9:00 pm AA1939 American Airlines Orlando — Charlotte 1h 15m stop 10:15 pm — 11:43 pm AA5273 American Airlines Charlotte — Des Moines	5h 26m including layover	Find flight from$104
8:27 am — 2:40 pm	8:27 am — 10:14 am AA461 American Airlines Orlando — Charlotte 2h 56m stop 1:10 pm — 2:40 pm AA5192 American Airlines Charlotte — Des Moines	7h 13m including layover	Find flight from$104
9:07 am — 4:34 pm	9:07 am — 11:03 am AA2075 American Airlines Orlando — Dallas 3h 41m stop 2:44 pm — 4:34 pm AA2388 American Airlines Dallas — Des Moines	8h 27m including layover	Find flight from$105
10:19 am — 8:50 pm	10:19 am — 12:03 pm AA2114 American Airlines Orlando — Charlotte 2h 26m stop 2:29 pm — 4:15 pm AA2034 American Airlines Charlotte — Philadelphia 2h 34m stop 6:49 pm — 8:50 pm AA4596 American Airlines Philadelphia — Des Moines	11h 31m including layover	Find flight from$108
11:55 am — 8:50 pm	11:55 am — 1:39 pm AA1849 American Airlines Orlando — Charlotte 50m stop 2:29 pm — 4:15 pm AA2034 American Airlines Charlotte — Philadelphia 2h 34m stop 6:49 pm — 8:50 pm AA4596 American Airlines Philadelphia — Des Moines	9h 55m including layover	Find flight from$108
12:03 pm — 6:33 pm	12:03 pm — 1:46 pm AA1849 American Airlines Orlando — Charlotte 57m stop 2:43 pm — 3:54 pm AA1883 American Airlines Charlotte — Chicago 1h 16m stop 5:10 pm — 6:33 pm AA3455 American Airlines Chicago — Des Moines	7h 30m including layover	Find flight from$160
12:03 pm — 9:43 pm	12:03 pm — 1:46 pm AA1849 American Airlines Orlando — Charlotte 59m stop 2:45 pm — 4:15 pm AA443 American Airlines Charlotte — Washington D.C. 3h 50m stop 8:05 pm — 9:43 pm AA4518 American Airlines Washington D.C. — Des Moines	10h 40m including layover	Find flight from$201
1:24 pm — 0:03 am +1 day	1:24 pm — 4:02 pm AA278 American Airlines Orlando — New York 3h 28m stop 7:30 pm — 9:40 pm AA574 American Airlines New York — Charlotte 55m stop 10:35 pm — 0:03 am AA5273 American Airlines Charlotte — Des Moines	11h 39m including layover	Find flight from$256
1:59 pm — 10:05 pm	1:59 pm — 3:42 pm AA1695 American Airlines Orlando — Charlotte 2h 17m stop 5:59 pm — 7:16 pm AA2488 American Airlines Charlotte — Chicago 1h 24m stop 8:40 pm — 10:05 pm AA3495 American Airlines Chicago — Des Moines	9h 6m including layover	Find flight from$249
3:35 pm — 11:43 pm	3:35 pm — 4:49 pm AA1362 American Airlines Orlando — Miami 1h 2m stop 5:51 pm — 8:00 pm AA1698 American Airlines Miami — Charlotte 2h 15m stop 10:15 pm — 11:43 pm AA5273 American Airlines Charlotte — Des Moines	9h 8m including layover	Find flight from$109
4:23 pm — 11:43 pm	4:23 pm — 6:54 pm AA1848 American Airlines Orlando — Philadelphia 33m stop 7:27 pm — 9:16 pm AA756 American Airlines Philadelphia — Charlotte 59m stop 10:15 pm — 11:43 pm AA5273 American Airlines Charlotte — Des Moines	8h 20m including layover	Find flight from$256
5:06 am — 11:08 am	5:06 am — 6:38 am AA2090 American Airlines Orlando — Charlotte 58m stop 7:36 am — 8:48 am AA462 American Airlines Charlotte — Chicago 1h 2m stop 9:50 am — 11:08 am AA3064 American Airlines Chicago — Des Moines	7h 2m including layover	Find flight from$102
8:34 am — 4:34 pm	8:34 am — 9:44 am AA2657 American Airlines Orlando — Miami 1h 31m stop 11:15 am — 1:28 pm AA1042 American Airlines Miami — Dallas 1h 16m stop 2:44 pm — 4:34 pm AA2388 American Airlines Dallas — Des Moines	9h including layover	Find flight from$109
9:59 am — 4:20 pm	9:59 am — 11:11 am AA1248 American Airlines Orlando — Miami 49m stop 12:00 pm — 2:22 pm AA132 American Airlines Miami — Chicago 38m stop 3:00 pm — 4:20 pm AA2995 American Airlines Chicago — Des Moines	7h 21m including layover	Find flight from$202

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times are local. Last updated on 01/20/2025

Flight Information

There are 127 flights by American Airlines from Orlando to Des Moines every week with departures from Orlando Int., Walt Disney World, Herndon. All flights arrive at Des Moines International Airport.

Departures start from 10:00 am to 9:59 am. Nonstop flight is 5h 21m. The time difference between Orlando and Des Moines is 1h.

The fastest flight 5h 21m
Average flight time 9h 39m
The earliest flight 10:00 am
The latest flight 9:59 am
Distance 1141 ml

The cheapest flight by American Airlines that our users were able to find is $102. This airfare is economy class on one-way AA2090 flight for October 3, 2018 leaving Orlando Int. in Orlando at 5:06 am, it includes all taxes and additional fees.

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American Airlines Airplanes on the Route

List of the most popular American Airlines airplanes flying from Orlando to Des Moines:

Airbus A321

from $102

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Boeing 737-800

from $104

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Boeing 737

from $105

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Airbus A319

from $146

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Other Popular Airlines on the Route

Besides American Airlines there are other 3 airline carriers between Orlando and Des Moines. Please review schedules and prices from the most popular airlines to find the best airfare deals from Orlando to Des Moines.

Nonstop flights

There’re no direct flights on this route. Try flights with stops.

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Connecting Flights

List of flights with layovers (1 and more stops):

UA - United Airlines

from $235

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XP - Casino Express

from $259

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NK - Spirit Airlines

from $134

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