American Airlines Detroit to San Francisco Flights

Cheapflightsplus.com will find cheap American Airlines flights from Detroit to San Francisco. Compare airline ticket prices and book air tickets starting from $53 from trusted online travel agencies, web sites and directly from airlines. Check flights schedule of American Airlines, arrivals and departure details below.

Find Cheap Airfare Detroit (MI) — San Francisco (CA) by American Airlines

To find cheap tickets choose a day of your departure with attractive price on the graph below and click «Find flights». For round trip flights please click «Check prices for return flight». The cheapest airfare is in may: one-way - $53, two-way – $91.
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Below is a detailed 2024 flight schedule for today, tomorrow and all other days. It may vary depending on season and a day of the week of your desired trip. We recommend booking your itinerary at least 2 weeks prior your travel to get the best price and availability by the airline.
Departure Arrival Flight Details Flight Time Price
10:59 am — 5:05 pm
10:59 am — 11:12 am AA2998 American Airlines
Detroit — Chicago
3h 18m stop
2:30 pm — 5:05 pm AA2639 American Airlines
Chicago — San Francisco
9h 6m
including layover
Find flight
from$54
11:46 am — 7:06 pm
11:46 am — 1:38 pm AA1940 American Airlines
Detroit — Charlotte
2h 56m stop
4:34 pm — 7:06 pm AA1659 American Airlines
Charlotte — San Francisco
10h 20m
including layover
Find flight
from$53
11:48 am — 6:55 pm
11:48 am — 1:37 pm AA1998 American Airlines
Detroit — Charlotte
2h 53m stop
4:30 pm — 6:55 pm AA1659 American Airlines
Charlotte — San Francisco
10h 7m
including layover
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from$53
12:04 pm — 5:05 pm
12:04 pm — 12:17 pm AA2972 American Airlines
Detroit — Chicago
2h 13m stop
2:30 pm — 5:05 pm AA2639 American Airlines
Chicago — San Francisco
8h 1m
including layover
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from$57
1:28 pm — 6:37 pm
1:28 pm — 3:15 pm AA637 American Airlines
Detroit — Charlotte
1h stop
4:15 pm — 6:37 pm AA1659 American Airlines
Charlotte — San Francisco
8h 9m
including layover
Find flight
from$66
2:18 pm — 10:38 pm
2:18 pm — 4:08 pm AA3421 American Airlines
Detroit — New York
3h 2m stop
7:10 pm — 10:38 pm AS1195 Alaska Airlines
New York — San Francisco
11h 20m
including layover
Find flight
from$764
2:46 pm — 9:02 pm
2:46 pm — 4:34 pm AA4921 American Airlines
Detroit — Philadelphia
1h 11m stop
5:45 pm — 9:02 pm AA547 American Airlines
Philadelphia — San Francisco
9h 16m
including layover
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from$450
3:30 pm — 8:53 pm
3:30 pm — 5:20 pm AA642 American Airlines
Detroit — Charlotte
1h 5m stop
6:25 pm — 8:53 pm AA1783 American Airlines
Charlotte — San Francisco
8h 23m
including layover
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from$53
4:40 pm — 11:19 pm
4:40 pm — 5:13 pm AA3076 American Airlines
Detroit — Chicago
3h 22m stop
8:35 pm — 11:19 pm AA2374 American Airlines
Chicago — San Francisco
9h 39m
including layover
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from$240
5:45 am — 9:45 am
5:45 am — 6:55 am AA442 American Airlines
Detroit — Phoenix
45m stop
7:40 am — 9:45 am AA1880 American Airlines
Phoenix — San Francisco
7h
including layover
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from$54
5:55 pm — 10:29 pm
5:55 pm — 7:05 pm AA2100 American Airlines
Detroit — Phoenix
1h 24m stop
8:29 pm — 10:29 pm AA597 American Airlines
Phoenix — San Francisco
7h 34m
including layover
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from$54
6:19 am — 2:07 pm
6:19 am — 8:10 am AA647 American Airlines
Detroit — Charlotte
3h 25m stop
11:35 am — 2:07 pm AA2061 American Airlines
Charlotte — San Francisco
10h 48m
including layover
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from$53
6:29 am — 11:52 am
6:29 am — 8:18 am AA647 American Airlines
Detroit — Charlotte
1h 12m stop
9:30 am — 11:52 am AA1956 American Airlines
Charlotte — San Francisco
8h 23m
including layover
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from$53
8:06 am — 2:07 pm
8:06 am — 10:01 am AA1642 American Airlines
Detroit — Charlotte
1h 34m stop
11:35 am — 2:07 pm AA2061 American Airlines
Charlotte — San Francisco
9h 1m
including layover
Find flight
from$53
10:59 am — 4:39 pm
10:59 am — 11:12 am AA2998 American Airlines
Detroit — Chicago
48m stop
12:00 pm — 2:21 pm AA2744 American Airlines
Chicago — Los Angeles
1h 9m stop
3:30 pm — 4:39 pm AA3163 American Airlines
Los Angeles — San Francisco
8h 40m
including layover
Find flight
from$53
12:04 pm — 7:39 pm
12:04 pm — 12:17 pm AA3004 American Airlines
Detroit — Chicago
2h 43m stop
3:00 pm — 5:21 pm AA1375 American Airlines
Chicago — Los Angeles
1h 9m stop
6:30 pm — 7:39 pm AA1095 American Airlines
Los Angeles — San Francisco
10h 35m
including layover
Find flight
from$53
1:28 pm — 9:58 pm
1:28 pm — 3:15 pm AA637 American Airlines
Detroit — Charlotte
1h 25m stop
4:40 pm — 6:41 pm AA707 American Airlines
Charlotte — Los Angeles
1h 49m stop
8:30 pm — 9:58 pm AA2998 American Airlines
Los Angeles — San Francisco
11h 30m
including layover
Find flight
from$66
3:25 pm — 10:39 pm
3:25 pm — 5:16 pm AA2559 American Airlines
Detroit — Dallas
1h 39m stop
6:55 pm — 8:12 pm AA2354 American Airlines
Dallas — Los Angeles
1h 18m stop
9:30 pm — 10:39 pm AA3151 American Airlines
Los Angeles — San Francisco
10h 14m
including layover
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from$53
4:38 pm — 0:15 am
+1 day
4:38 pm — 5:10 pm AA3076 American Airlines
Detroit — Chicago
1h 25m stop
6:35 pm — 9:04 pm AA2715 American Airlines
Chicago — Los Angeles
1h 46m stop
10:50 pm — 0:15 am AA6020 American Airlines
Los Angeles — San Francisco
10h 37m
including layover
Find flight
from$291
7:40 am — 4:39 pm
7:40 am — 9:28 am AA2491 American Airlines
Detroit — Dallas
3h 2m stop
12:30 pm — 1:47 pm AA1331 American Airlines
Dallas — Los Angeles
1h 43m stop
3:30 pm — 4:39 pm AA3163 American Airlines
Los Angeles — San Francisco
11h 59m
including layover
Find flight
from$53
7:40 am — 1:39 pm
7:40 am — 9:28 am AA2491 American Airlines
Detroit — Dallas
52m stop
10:20 am — 11:37 am AA1085 American Airlines
Dallas — Los Angeles
53m stop
12:30 pm — 1:39 pm AA497 American Airlines
Los Angeles — San Francisco
8h 59m
including layover
Find flight
from$53
8:45 am — 4:39 pm
8:45 am — 8:58 am AA3181 American Airlines
Detroit — Chicago
1h 17m stop
10:15 am — 12:36 pm AA333 American Airlines
Chicago — Los Angeles
2h 54m stop
3:30 pm — 4:39 pm AA3183 American Airlines
Los Angeles — San Francisco
10h 54m
including layover
Find flight
from$53
*Departure and arrival times are local. Last updated on 05/07/2024

Flight Information

There are 147 flights by American Airlines from Detroit to San Francisco every week with departures from Detroit City and Willow Run. All flights arrive at San Francisco, Embarkadero, China Basin Heliport.

Departures start from 10:14 am to 8:45 am. Nonstop flight is 6h 54m. The time difference between Detroit and San Francisco is 3h.

  • The fastest flight 6h 54m
  • Average flight time 9h 41m
  • The earliest flight 10:14 am
  • The latest flight 8:45 am
  • Distance 2090 ml

The cheapest flight by American Airlines that our users were able to find is $53. This airfare is economy class on one-way AA642 flight for October 8, 2020 leaving All airports in Detroit at 3:30 pm, it includes all taxes and additional fees.

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Other Popular Airlines on the Route

Besides American Airlines there are other 6 airline carriers between Detroit and San Francisco. Please review schedules and prices from the most popular airlines to find the best airfare deals from Detroit to San Francisco.

Nonstop flights

There are 12 direct flights every day from Detroit. Airlines and fares are below:

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Connecting Flights

List of flights with layovers (1 and more stops):

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How to book an air ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected airfare.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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